3M Delivers Early Purification with New Hybrid Purifiers


Single-use functionalised media provides scalable purification performance in cell culture

Bracknell, UK, 7 February 2014 – Diversified technology company 3M today announced the launch of a new purification and separation product for biopharmaceutical processes. The Emphaze AEX Hybrid Purifier by 3M encapsulates an anionic exchange (AEX) media with a downstream micro-porous membrane for single-use manufacturing. The scalable range will be suitable for process development through to large scale cell culture.

Lynne Deakin, Scientific Application Specialist at 3M Purification division, will be presenting the Emphaze AEX Hybrid Purifier at 3pm on Day 1 of the 7th Annual BioInnovation Leaders Summit, 10-11 February 2014 in London.

Emphaze AEX Hybrid Purifiers address the requirement for high purity as early as possible in the manufacturing process. Using innovative anionic ligand technology, the purifier delivers chromatographic adsorption capabilities to reduce soluble and insoluble contaminants that are typically removed by Protein A columns and subsequent purification stages such as host cell proteins (HCP), host cell DNA, and endotoxin. Rapid pressure build on the 0.2um bioburden membrane downstream of the functionalised media signals when ion exchange capacity is saturated, helping to protect against breakthrough of impurities. Early removal of soluble impurities lessens the impact on expensive downstream purification technologies such as the Protein A column.

Emphaze AEX Hybrid Purifiers are easy to use, scalable and offer reproducible performance as there is no scope for channelling or mixing as seen with mobile media. The range is fully disposable eliminating the need for cleaning validation and can be retrofitted into existing hardware platforms.

Hear more about Emphaze AEX Hybrid Purifiers from 3M Lynne Deakin at the BioInnovation Leaders Summit or visit www.3M.co.uk/filtration .

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3M and Emphaze are trademarks of 3M Company.

About 3M

3M captures the spark of new ideas and transforms them into thousands of ingenious products.

Our culture of creative collaboration inspires a never-ending stream of powerful technologies, creating innovative products that help make the world healthier, safer and more productive. Well known 3M brands include Scotch, Post-it, Scotchgard, Thinsulate and Scotch-Brite.

With $30 billion in sales, 3M employs 88,000 people worldwide and has operations in more than 70 countries. The UK and Ireland is home to one of the largest 3M subsidiaries outside the USA, employing more than 3,000 people across 19 locations, including nine manufacturing sites.

Products manufactured in the UK include coated abrasives, personal safety equipment, adhesive tapes, industrial microbiology products, drug delivery systems, high-performance coatings, secure documents, passport readers and imaging systems.

For more information, visit www.3M.co . uk or follow @3M_UK on Twitter.

Press contacts:

Katherine Barnicoat                                  Beky Cann

3M Purification Division                            Neesham Public Relations

Tel: +44 (0) 1344 858437                         Tel: +44 (0) 1296 628180

Email: kfbarnicoat@mmm.com                 Email: bekyc@neesham.co.uk

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About Us

About 3M3M captures the spark of new ideas and transforms them into thousands of ingenious products. Its culture of creative collaboration inspires a never-ending stream of powerful technologies that make life better. The $27 billion diversified technology company has, since 1902, been creating innovative products that help make the world healthier, safer and more productive. Well known 3M brands include Scotch, Post-it, Scotchgard, Thinsulate and Scotch-Brite. 3M employs some 80,000 people worldwide and has operations in more than 65 countries. The UK and Ireland is home to one of the largest 3M subsidiaries outside the USA, employing more than 3,500 people across 19 locations, including 10 manufacturing sites. Products manufactured in the UK include coated abrasives, occupational health and environmental safety equipment, adhesive tapes, industrial microbiology products, drug delivery systems, high-performance coatings, secure documents and passport scanners.

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