3M Delivers Early Purification with New Hybrid Purifiers
Single-use functionalised media provides scalable purification performance in cell culture
Bracknell, UK, 7 February 2014 – Diversified technology company 3M today announced the launch of a new purification and separation product for biopharmaceutical processes. The Emphaze AEX Hybrid Purifier by 3M encapsulates an anionic exchange (AEX) media with a downstream micro-porous membrane for single-use manufacturing. The scalable range will be suitable for process development through to large scale cell culture.
Lynne Deakin, Scientific Application Specialist at 3M Purification division, will be presenting the Emphaze AEX Hybrid Purifier at 3pm on Day 1 of the 7th Annual BioInnovation Leaders Summit, 10-11 February 2014 in London.
Emphaze AEX Hybrid Purifiers address the requirement for high purity as early as possible in the manufacturing process. Using innovative anionic ligand technology, the purifier delivers chromatographic adsorption capabilities to reduce soluble and insoluble contaminants that are typically removed by Protein A columns and subsequent purification stages such as host cell proteins (HCP), host cell DNA, and endotoxin. Rapid pressure build on the 0.2um bioburden membrane downstream of the functionalised media signals when ion exchange capacity is saturated, helping to protect against breakthrough of impurities. Early removal of soluble impurities lessens the impact on expensive downstream purification technologies such as the Protein A column.
Emphaze AEX Hybrid Purifiers are easy to use, scalable and offer reproducible performance as there is no scope for channelling or mixing as seen with mobile media. The range is fully disposable eliminating the need for cleaning validation and can be retrofitted into existing hardware platforms.
Hear more about Emphaze AEX Hybrid Purifiers from 3M Lynne Deakin at the BioInnovation Leaders Summit or visit www.3M.co.uk/filtration .
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Katherine Barnicoat Beky Cann
3M Purification Division Neesham Public Relations
Tel: +44 (0) 1344 858437 Tel: +44 (0) 1296 628180