According to the latest research, up to 30% of the performance response seen in broilers following phytase superdosing may be due to the beneficial effects of the inositol released following complete phytate degradation.

Inositol is produced when all six of the phosphate (P) ions contained within phytate, otherwise known as inositol hexaphosphate (IP6), have been stripped away by the combined action of phytase and endogenous phosphatases. The resulting inositol appears critical to successful superdosing, and its production relies heavily on achieving greater than 85% destruction of both phytate and its lower esters (IP5 through to IP1), claims Dr Mike Bedford, AB Vista’s Research Director.

“The growth-promoting effects of inositol in chicks have been recognised since the 1940s,” he states. “Inositol is known to have important metabolic roles, such as in fat metabolism and cell function, as well as being combined with phosphorus at a cellular level to recreate phytate, which is a potent anti-oxidant.

“What we have now been able to show is that inositol accounts for around 30% of the improvement in feed conversion ratio (FCR) seen in broilers when superdosing with a new generation E.coli phytase*, regardless of whether the diet is deficient in P or not.”

Targeting the necessary level of phytate destruction, and subsequent inositol production, is therefore vital. It also puts a strong focus on the phytase characteristics needed to achieve that goal, according to Dr Bedford.

“A high rate of activity at the low pH found in the stomach is critical, as is an ability to continue phytate breakdown even when concentrations are low, to maximise phytate destruction,” he highlights.

“It is also important the  phytase can survive high temperature feed processing without the need for coating, which may slow the onset of activity in the stomach, and be able to withstand the bird’s own digestive enzymes long enough to be effective.”

* Quantum Blue

For more information, contact AB Vista on +44(0)1672 517 650 or


Notes to editor:

AB Vista is a leading global supplier of micro-ingredients for the animal feed industry.

For further press information please contact Nic Daley or Mike Keeler on +44 (0)20 8647 4467.



About Us

AB Vista is an animal nutrition technology company offering pioneering products and technical services to the global animal feed industry. Since its establishment in 2004, AB Vista has grown to be a top-three player in feed enzymes and is also one of the largest suppliers of natural betaine to the global animal nutrition industry. The company invests heavily in research and development and has a growing portfolio of products and services spanning the poultry, swine, ruminant and aquaculture sectors. AB Vista is headquartered in the UK, with regional offices located in the USA, Brazil, Singapore, Spain, India, China, Germany and Finland. AB Vista is part of AB Agri, the agricultural division of Associated British Foods, one of Europe’s largest food & retail companies with a market capitalisation of £22 billion.

Documents & Links