COMPANIES ACT 1985 SECTION 198 DISCLOSURE OF INTEREST IN VOTING SHARES IN PUBLIC COMPANIES

COMPANIES ACT 1985 SECTION 198 DISCLOSURE OF INTEREST IN VOTING SHARES IN PUBLIC COMPANIES On 1 October 2004 we were informed that, as of 29 September 2004, Barclays PLC had a notifiable interest in the USD0.25 ordinary shares of AstraZeneca PLC 50,634,731 shares which represents 3.05 per cent of the issued ordinary capital of the company. G H R Musker Company Secretary 1 October 2004 ------------------------------------------------------------ This information was brought to you by Waymaker http://www.waymaker.net The following files are available for download: http://www.waymaker.net/bitonline/2004/10/01/20041001BIT00240/wkr0001.pdf

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AstraZeneca is a global, innovation-driven biopharmaceutical business with a primary focus on the discovery, development and commercialisation of prescription medicines. As a leader in gastrointestinal, cardiovascular, neuroscience, respiratory and inflammation, oncology and infectious disease medicines, AstraZeneca generated global revenues of US $32.8 billion in 2009. For more information please visit: www.astrazeneca.com

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