﻿<?xml version="1.0" encoding="utf-8"?><rss version="2.0" xmlns:media="http://search.yahoo.com/mrss/"><channel><title>Cision News</title><link>https://news.cision.com</link><description>Cision is the leading global provider of media research, distribution, monitoring and evaluation services. With over 40 locations throughout the world, Cision provides the insight, expertise and intelligence that improve performance and build reputations.</description><pubDate>Tue, 09 Jun 2026 13:00:42 GMT</pubDate><image><title>Cision News</title><width>146</width><height>60</height><link>https://news.cision.com</link><url>https://news.cision.com/Content/img/news-logo.png</url></image><item><title>Admission of Further Securities to Trading</title><link>https://news.cision.com/astrazeneca/r/admission-of-further-securities-to-trading,c4355941</link><guid isPermaLink="false">cision5374658</guid><description><![CDATA[1 June 2026

Notification of Admission of Further Securities to Trading (PRM 1.6.4R)

The following notification is made in accordance with The Public Offers and Admissions to Trading Regulations 2024 (POATRs) PRM 1.6.4R.

1   Details of the issuer
a)  Name                        AstraZeneca PLC
b)  LEI                         PY6ZZQWO2IZFZC3IOL08
2   Details of the transferable
    securities admitted to
    trading
a)  Name, type and              Ordinary Shares of $0.25
    identification code         eachISIN: GB0009895292
b)  Regulated market            London Stock]]></description><pubDate>Mon, 01 Jun 2026 14:05:00 GMT</pubDate></item><item><title>Total Voting Rights</title><link>https://news.cision.com/astrazeneca/r/total-voting-rights,c4355955</link><guid isPermaLink="false">cision5374649</guid><description><![CDATA[1 June 2026

Total Voting Rights

The following notification is made in accordance with the UK Financial Conduct Authority's Disclosure and Transparency Rule 5.6.1. As at 31 May 2026 the issued share capital of AstraZeneca PLC with voting rights is 1,551,009,750 ordinary shares of US$0.25. No shares are held in Treasury. Therefore, the total number of voting rights in AstraZeneca PLC is 1,551,009,750.

The above figure for the total number of voting rights may be used by shareholders as the denominator for the calculations by which they will determine if they are required to notify]]></description><pubDate>Mon, 01 Jun 2026 14:00:00 GMT</pubDate></item><item><title>Imfinzi approved in US for early bladder cancer</title><link>https://news.cision.com/astrazeneca/r/imfinzi-approved-in-us-for-early-bladder-cancer,c4354945</link><guid isPermaLink="false">cision5373021</guid><description><![CDATA[29 May 2026

 

Imfinzi approved in the US in first and only immunotherapy combination for patients with BCG-naïve, high-risk non-muscle-invasive bladder cancer

 

Based on POTOMAC Phase III trial results which showed a 32% reduction in the risk of high-risk disease recurrence, progression or death after one year of Imfinzi added to BCG vs. BCG alone

                                           

AstraZeneca's Imfinzi (durvalumab) in combination with Bacillus Calmette-Guérin (BCG) induction and maintenance therapy has been approved in the US for the treatment of adult patients]]></description><pubDate>Fri, 29 May 2026 06:00:00 GMT</pubDate></item><item><title>US FDA decision date on camizestrant extended</title><link>https://news.cision.com/astrazeneca/r/us-fda-decision-date-on-camizestrant-extended,c4353645</link><guid isPermaLink="false">cision5370934</guid><description><![CDATA[27 May 2026

US FDA decision date extended for SERENA-6 filing of camizestrant to enable review of additional data

The US Food and Drug Administration (FDA) has informed AstraZeneca that it will extend the Prescription Drug User Fee Act (PDUFA) date to review additional data requested to support the New Drug Application (NDA) for camizestrant in combination with a cyclin-dependent kinase (CDK) 4/6 inhibitor (palbociclib, ribociclib or abemaciclib) for the 1st-line treatment of patients with hormone receptor (HR)-positive, HER2-negative advanced breast cancer whose tumours have an]]></description><pubDate>Wed, 27 May 2026 06:00:00 GMT</pubDate></item><item><title>Datroway approved in US for 1L triple-negative BC</title><link>https://news.cision.com/astrazeneca/r/datroway-approved-in-us-for-1l-triple-negative-bc,c4352964</link><guid isPermaLink="false">cision5369792</guid><description><![CDATA[26 May 2026

 

Datroway approved in the US as first TROP2-directed antibody drug conjugate for 1st-line treatment of patients with metastatic triple-negative breast cancer who are not PD-1/PD-L1 inhibitor candidates

AstraZeneca and Daiichi Sankyo's Datroway is the only TROP2-directed antibody drug conjugate to prolong overall survival in this setting vs. chemotherapy, with an unprecedented median overall survival of approximately two years based on the TROPION-Breast02 Phase III trial

 

Datroway has the potential to become the new standard of care in this setting]]></description><pubDate>Tue, 26 May 2026 06:00:00 GMT</pubDate></item><item><title>Enhertu recommended in EU for HER2+ solid tumours</title><link>https://news.cision.com/astrazeneca/r/enhertu-recommended-in-eu-for-her2--solid-tumours,c4352965</link><guid isPermaLink="false">cision5369794</guid><description><![CDATA[26 May 2026

Enhertu recommended for approval in the EU by CHMP for patients with previously treated HER2-positive metastatic solid tumours

Based on three Phase II trials of AstraZeneca and Daiichi Sankyo's Enhertu which showed clinically meaningful responses across a broad range of tumours

If approved, Enhertu would become the first HER2-directed therapy and

antibody drug conjugate to receive a tumour agnostic indication in the EU

 

AstraZeneca and Daiichi Sankyo's Enhertu (trastuzumab deruxtecan) has been recommended for approval in the European Union (EU) as a]]></description><pubDate>Tue, 26 May 2026 06:00:00 GMT</pubDate></item><item><title>Camizestrant recommended for breast cancer in EU</title><link>https://news.cision.com/astrazeneca/r/camizestrant-recommended-for-breast-cancer-in-eu,c4352967</link><guid isPermaLink="false">cision5369796</guid><description><![CDATA[26 May 2026

 

Camizestrant in combination with a CDK4/6 inhibitor recommended for approval in the EU by CHMP for 1st-line advanced ER-positive breast cancer

Recommendation based on SERENA-6 Phase III trial results which showed combination reduced the risk of disease progression or death by 56% in patients with an emergent ESR1 tumour mutation

If approved, camizestrant has the potential to reshape 1st-line treatment for patients in Europe with this type of advanced breast cancer

AstraZeneca's camizestrant in combination with a cyclin-dependent kinase (CDK) 4/6 inhibitor (]]></description><pubDate>Tue, 26 May 2026 06:00:00 GMT</pubDate></item><item><title>Director/PDMR Shareholding</title><link>https://news.cision.com/astrazeneca/r/director-pdmr-shareholding,c4349603</link><guid isPermaLink="false">cision5364861</guid><description><![CDATA[18 May 2026

 

 

Transaction by Person Discharging Managerial Responsibilities

 

 

AstraZeneca PLC (the Company) announced that, on 14 May 2026, an award of the Company's ordinary shares of $0.25 each (Ordinary Shares) vested to Pascal Soriot, Executive Director and Chief Executive Officer, under the terms of the AstraZeneca Performance Share Plan (AZPSP).

 

The AZPSP award was granted on 14 May 2021 as part of the award granted to Mr Soriot on 5 March 2021, and reflected the revised limits of the AZPSP, as approved by shareholders at the Company's 2021 Annual General]]></description><pubDate>Mon, 18 May 2026 14:00:00 GMT</pubDate></item><item><title>Enhertu approved in two HER2+ early BC settings</title><link>https://news.cision.com/astrazeneca/r/enhertu-approved-in-two-her2--early-bc-settings,c4349368</link><guid isPermaLink="false">cision5364208</guid><description><![CDATA[18 May 2026

Enhertu approved in the US for two new indications for patients with HER2-positive early breast cancer

Approved for use before surgery based on DESTINY-Breast11 Phase III trial

Approved for use following surgery based on DESTINY-Breast05 Phase III trial

Two new indications bring AstraZeneca and Daiichi Sankyo's Enhertu into curative-intent setting, reinforcing its role across stages of HER2-positive breast cancer

AstraZeneca and Daiichi Sankyo's Enhertu (trastuzumab deruxtecan) has been approved by the US Food and Drug Administration (FDA) for both the neoadjuvant]]></description><pubDate>Mon, 18 May 2026 06:05:00 GMT</pubDate></item><item><title>Baxfendy approved in the US for hypertension</title><link>https://news.cision.com/astrazeneca/r/baxfendy-approved-in-the-us-for-hypertension,c4349370</link><guid isPermaLink="false">cision5364181</guid><description><![CDATA[18 May 2026

Baxfendyapproved in the US as the first and only aldosterone synthase inhibitortreatment for adults with hypertension

Approval based on BaxHTN Phase III results showing statistically significant and clinically meaningful reduction in systolic blood pressure in patients with uncontrolled or resistant hypertension

Baxfendy 2mg lowered systolic blood pressure by 15.7 mmHg (9.8 mmHg placebo-adjusted) from baseline in BaxHTN trial

AstraZeneca's Baxfendy (baxdrostat) has been approved in the US as a first-in-class aldosterone synthase inhibitor (ASI) for the treatment of]]></description><pubDate>Mon, 18 May 2026 06:00:00 GMT</pubDate></item><item><title>Imfinzi + EV improves EFS &amp; OS in bladder cancer</title><link>https://news.cision.com/astrazeneca/r/imfinzi---ev-improves-efs---os-in-bladder-cancer,c4348672</link><guid isPermaLink="false">cision5363288</guid><description><![CDATA[14 May 2026

Perioperative Imfinzi plus neoadjuvant EV showed statistically significant and clinically meaningful improvements in event-free survival and overall survival in muscle-invasive bladder cancer in the Phase III VOLGA trial

Perioperative Imfinzi plus Imjudo and neoadjuvant EV showed a statistically significant and clinically meaningful improvement in event-free survival and a favourable trend for overall survival

High-level results from a planned interim analysis of the VOLGA Phase III trial showed perioperative treatment with Imfinzi (durvalumab) in combination with]]></description><pubDate>Thu, 14 May 2026 06:00:00 GMT</pubDate></item><item><title>Total Voting Rights and Admission of Shares</title><link>https://news.cision.com/astrazeneca/r/total-voting-rights-and-admission-of-shares,c4343483</link><guid isPermaLink="false">cision5355344</guid><description><![CDATA[1 May 2026

Total Voting Rights and Notification of Admission of Further Securities to Trading (PRM 1.6.4R)

Total Voting Rights

The following notification is made in accordance with the UK Financial Conduct Authority's Disclosure and Transparency Rule 5.6.1. As at 30 April 2026 the issued share capital of AstraZeneca PLC with voting rights is 1,550,995,630 ordinary shares of US$0.25. No shares are held in Treasury. Therefore, the total number of voting rights in AstraZeneca PLC is 1,550,995,630.

The above figure for the total number of voting rights may be used by shareholders as]]></description><pubDate>Fri, 01 May 2026 14:00:00 GMT</pubDate></item><item><title>FDA ODAC vote on camizestrant in breast cancer</title><link>https://news.cision.com/astrazeneca/r/fda-odac-vote-on-camizestrant-in-breast-cancer,c4343408</link><guid isPermaLink="false">cision5355179</guid><description><![CDATA[01 May 2026

Update on FDA Advisory Committee vote on camizestrant in combination with a CDK4/6 inhibitor for advanced HR-positive breast cancer

The US Food and Drug Administration's (FDA) Oncologic Drugs Advisory Committee (ODAC) did not reach a majority vote in favor of the benefit risk profile of AstraZeneca's camizestrant in combination with a cyclin-dependent kinase (CDK) 4/6 inhibitor (palbociclib, ribociclib or abemaciclib) for the 1st-line treatment of patients with hormone receptor (HR)-positive, HER2-negative advanced breast cancer whose tumours have an emergent ESR1 mutation,]]></description><pubDate>Fri, 01 May 2026 06:05:00 GMT</pubDate></item><item><title>FDA ODAC recommends Truqap in prostate cancer</title><link>https://news.cision.com/astrazeneca/r/fda-odac-recommends-truqap-in-prostate-cancer,c4343405</link><guid isPermaLink="false">cision5355170</guid><description><![CDATA[01 May 2026

Truqap recommended by FDA Advisory Committee for PTEN-deficient metastatic hormone-sensitive prostate cancer

ODAC overwhelming majority voted that Truqap plus abiraterone and ADT demonstrated a favourable benefit risk profile for patients based on the CAPItello-281 Phase III trial results

First and only targeted treatment combination to demonstrate benefit in this subtype of prostate cancer addresses significant unmet patient need

The US Food and Drug Administration's (FDA) Oncologic Drugs Advisory Committee (ODAC) has recognised a favourable benefit risk profile for]]></description><pubDate>Fri, 01 May 2026 06:00:00 GMT</pubDate></item><item><title>1st Quarter Results</title><link>https://news.cision.com/astrazeneca/r/1st-quarter-results,c4341878</link><guid isPermaLink="false">cision5352975</guid><description><![CDATA[29 April 2026

AstraZeneca results: Q1 2026

Strong revenue growth and positive readouts from high-value NMEs reinforce confidence in 2030 ambition

Revenue and EPS summary

[][]
                       Q1 2026           % Change
                            $m   Actual    CER[1]
 - Product Sales        14,386       12        7 
 - Alliance Revenue        825       29       26 
Product Revenue         15,211       13        8 
Collaboration Revenue       77        4        - 
Total Revenue           15,288       13        8 
Reported EPS ($)          1.99        6        8]]></description><pubDate>Wed, 29 Apr 2026 06:00:00 GMT</pubDate></item><item><title>Breztri approved in the US for asthma</title><link>https://news.cision.com/astrazeneca/r/breztri-approved-in-the-us-for-asthma,c4341023</link><guid isPermaLink="false">cision5351727</guid><description><![CDATA[28 April 2026

 

Breztri approved in the US for asthma as first and only triple therapy for patients 12 years of age and older

 

Approval based on KALOS and LOGOS Phase III trials demonstrating statistically significant and clinically meaningful benefits of AstraZeneca's single-inhaler fixed-dose triple therapy compared with inhaled dual therapy

 

Approval is second indication for Breztri beyond COPD   

 

AstraZeneca's fixed-dose triple-combination therapy Breztri Aerosphere (budesonide/glycopyrrolate/formoterol fumarate or BGF 320/36/9.6μg) has been approved in the]]></description><pubDate>Tue, 28 Apr 2026 06:27:26 GMT</pubDate></item><item><title>Saphnelo self-administration approved in the US</title><link>https://news.cision.com/astrazeneca/r/saphnelo-self-administration-approved-in-the-us,c4340319</link><guid isPermaLink="false">cision5350690</guid><description><![CDATA[27 April 2026

 

Saphnelo approved in the US for subcutaneous self-administration as a new autoinjector for the treatment of systemic lupus erythematosus

 

First-in-class Saphnelo Pen now offers greater flexibility and convenience, reaching a wider group of patients

 

AstraZeneca's Saphnelo (anifrolumab) has been approved in the US for self-administration as a once-weekly autoinjector, the Saphnelo Pen, for the treatment of adult patients with systemic lupus erythematosus (SLE) on top of standard therapy.

 

The approval by the US Food and Drug Administration (FDA) was]]></description><pubDate>Mon, 27 Apr 2026 06:00:00 GMT</pubDate></item><item><title>Directorate change</title><link>https://news.cision.com/astrazeneca/r/directorate-change,c4338932</link><guid isPermaLink="false">cision5348606</guid><description><![CDATA[23 April 2026

Change to AstraZeneca Board of Directors

 

AstraZeneca congratulates Rene Haas on his appointment as Chief Executive Officer of SoftBank Group International, in addition to his position as Chief Executive Officer of Arm Holdings plc. Taking into account this additional workload, we have mutually agreed that Rene will not have enough time available to fully assume his AstraZeneca Board member duties. He will step down as a Non-Executive Director of AstraZeneca PLC on 30 April 2026, as he takes up his new appointment.

 

Michel Demaré, Chair of AstraZeneca, said "]]></description><pubDate>Thu, 23 Apr 2026 06:00:00 GMT</pubDate></item><item><title>I CAN PhIII interim analysis met primary endpoint</title><link>https://news.cision.com/astrazeneca/r/i-can-phiii-interim-analysis-met-primary-endpoint,c4337443</link><guid isPermaLink="false">cision5346467</guid><description><![CDATA[21 April 2026

Ultomiris demonstrated statistically significant and clinically meaningful reduction of proteinuria in adults with immunoglobulin A nephropathy in

I CAN Phase III trial

Ultomiris delivered rapid reduction in proteinuria as early as week 10

Results show potential for terminal C5 complement inhibition with Ultomiris as a disease-modifying treatment option for IgAN

Positive high-level results from a prespecified interim analysis of the I CAN Phase III trial showed that Ultomiris (ravulizumab) met its primary endpoint, demonstrating a statistically significant and]]></description><pubDate>Tue, 21 Apr 2026 06:00:00 GMT</pubDate></item><item><title>Third tozorakimab positive Phase III in COPD</title><link>https://news.cision.com/astrazeneca/r/third-tozorakimab-positive-phase-iii-in-copd,c4336841</link><guid isPermaLink="false">cision5345689</guid><description><![CDATA[20 April 2026

Tozorakimab met primary endpoint in Phase III MIRANDA trial in patients with COPD

Third positive pivotal Phase III clinical trial of AstraZeneca's IL-33-targeting biologic further demonstrates its benefits in COPD

Positive high-level results from the pivotal Phase III MIRANDA trial showed potential first-in-class tozorakimab demonstrated a statistically significant and clinically meaningful reduction in the annualised rate of moderate-to-severe COPD exacerbations in the primary population of former smokers and in the overall population, which included former and]]></description><pubDate>Mon, 20 Apr 2026 06:00:00 GMT</pubDate></item><item><title>Result of AGM</title><link>https://news.cision.com/astrazeneca/r/result-of-agm,c4332902</link><guid isPermaLink="false">cision5340242</guid><description><![CDATA[9 April 2026

Results of Annual General Meeting held on 9 April 2026

AstraZeneca PLC announced the results of the voting at its Annual General Meeting (AGM) today. As proposed in the Notice of AGM, all Resolutions were decided by poll vote. Resolutions 10 - 13 were passed as special resolutions; all other resolutions were passed as ordinary resolutions.

     Resolution      Votes for     % of      Votes      % of   Votes cast in   Total     Votes
                                  votes     against    votes       total       votes    withheld
                                   cast]]></description><pubDate>Thu, 09 Apr 2026 16:25:12 GMT</pubDate></item><item><title>Imfinzi+Imjudo improves PFS in early liver cancer</title><link>https://news.cision.com/astrazeneca/r/imfinzi-imjudo-improves-pfs-in-early-liver-cancer,c4330517</link><guid isPermaLink="false">cision5336946</guid><description><![CDATA[2 April 2026

 Imfinzi plus Imjudo combined with lenvatinib and TACE demonstrated a statistically significant and clinically meaningful improvement in progression-free survival in embolisation-eligible unresectable liver cancer in EMERALD-3 Phase III trial

Imfinzi plus Imjudo combined with lenvatinib and transarterial chemoembolisation (TACE) showed trend toward improved overall survival

Positive high-level results from the EMERALD-3 Phase III trial showed AstraZeneca's Imfinzi (durvalumab) in combination with Imjudo (tremelimumab), lenvatinib and transarterial chemoembolisation (]]></description><pubDate>Thu, 02 Apr 2026 06:21:24 GMT</pubDate></item><item><title>Total Voting Rights and Admission of Shares</title><link>https://news.cision.com/astrazeneca/r/total-voting-rights-and-admission-of-shares,c4329740</link><guid isPermaLink="false">cision5336584</guid><description><![CDATA[1 April 2026

Total Voting Rights and Notification of Admission of Further Securities to Trading (PRM 1.6.4R)

Total Voting Rights

The following notification is made in accordance with the UK Financial Conduct Authority's Disclosure and Transparency Rule 5.6.1. As at 31 March 2026 the issued share capital of AstraZeneca PLC with voting rights is 1,550,980,823 ordinary shares of US$0.25. No shares are held in Treasury. Therefore, the total number of voting rights in AstraZeneca PLC is 1,550,980,823.

The above figure for the total number of voting rights may be used by shareholders]]></description><pubDate>Wed, 01 Apr 2026 14:00:00 GMT</pubDate></item><item><title>Efzimfotase alfa Ph3 program show positive results</title><link>https://news.cision.com/astrazeneca/r/efzimfotase-alfa-ph3-program-show-positive-results,c4329064</link><guid isPermaLink="false">cision5334708</guid><description><![CDATA[This announcement contains inside information

31 March 2026

Efzimfotase alfa demonstrated positive results from global Phase III clinical programme in hypophosphatasia

MULBERRY randomised, placebo-controlled trial showed efzimfotase alfa demonstrated statistically significant and clinically meaningful improvement in bone health in treatment-na•ve paediatric patients

CHESTNUT randomised, open-label, active-controlled trial demonstrated safety and tolerability of efzimfotase alfa in paediatric patients previously treated with Strensiq with maintenance of therapeutic benefit]]></description><pubDate>Tue, 31 Mar 2026 06:00:00 GMT</pubDate></item></channel></rss>