Head of Marketing and Business Development Strengthens Biacore's Executive Management Team

Head of Marketing and Business Development Strengthens Biacore's Executive Management Team Uppsala, Sweden, December 15, 2003. Biacore International AB (Biacore) (Stockholmsbörsen: BCOR; Nasdaq: BCOR) today announced the decision to establish a new position, Head of Marketing and Business Development, reporting to the President and Chief Executive Officer, and has appointed Mr Erik Walldén to fill this position: Mr Walldén will join Biacore on January 19, 2004, and will be based at the Company's head office at Neuchâtel, Switzerland. The Board of Directors has appointed Mr Waldén Executive Vice President in Biacore International AB. Ulf Jönsson, President and CEO, says: "The situation on the market has made 2003 a very tough year for Biacore with declining sales. This is not due to any lack of customers' satisfaction with our products or any price erosion due to competition but is mainly the result of a slowdown in the pharmaceutical industry's investments in the early phases of R&D. On this basis, we see a need to focus, strengthen our resources and change the structure of our marketing organization. In view of Erik Walldén's solid experience of marketing and business development, I am convinced that he will greatly contribute to a positive development for Biacore." Erik Walldén, born in 1949, has extensive experience from the biotech supply industry. After 13 years in various R&D and marketing positions within Pharmacia Biotechnology (today Amersham Biosciences), he was appointed vice president worldwide marketing, sales and support at Pharmacia Biosensor (name changed to Biacore in conjunction with the IPO) in 1989. In this position, he was responsible for establishing Biacore's marketing and sales organization, marketing communication and branding. From 1992 onwards Erik Walldén held a number of vice president positions, among others in PerSeptive Biosystems and Applied Biosystems in the United States. In 1998 he was appointed President and CEO of Pyrosequencing AB which he has managed from an early-stage start-up company to its present position as a publicly listed biotech supplier with global presence. Mr Walldén has an education in analytical chemistry and biochemistry (Uppsala University).. - Ends - About Biacore Biacore is a global market leader in Surface Plasmon Resonance (SPR) technology based systems with its own sales operations in the U.S., across Europe, Japan, Australia and New Zealand. A strong patent portfolio protects Biacore's SPR technology, which gives unique real- time insights into biomolecular interactions. Target groups for the Company's products consist primarily of medical and life science research laboratories and pharmaceutical and biotechnology companies around the world. Biacore is focusing on drug discovery and development as its prime areas for future growth. The Company currently has seven systems on the market, the most important of which are: Biacore®S51 for applications downstream of high-throughput screening (HTS) including rapid characterization of HTS hits and comprehensive pre-clinical evaluation of lead compounds, Biacore®3000, which offers flexibility in key life science research and drug discovery applications upstream of HTS, and Biacore®C which is specifically designed for compliant concentration analysis of biopharmaceuticals in GLP/GMP applications. A new [REMOVED GRAPHICS]SPR array chip system, which will provide higher information content, is expected to reach the market in 2004. Based in Uppsala, Sweden, the Company is listed on Stockholmsbörsen and Nasdaq in the U.S. In 2002 the Company had sales of SEK 614.2 million and an operating income of SEK 140.6 million. Further information on Biacore can be found on the web: www.biacore.com For further information, please contact: Ulf Jönsson, President and CEO +41 (0)79 668 8336 Scientific/Trade Press Enquiries: Sarah Perceval, De Facto Communications Michaels Mahon, De Facto Communications +44 (0) 207 496 3300 ------------------------------------------------------------ This information was brought to you by Waymaker http://www.waymaker.net The following files are available for download: http://www.waymaker.net/bitonline/2003/12/15/20031215BIT00300/wkr0001.doc http://www.waymaker.net/bitonline/2003/12/15/20031215BIT00300/wkr0002.pdf

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Biacore™ systems for label-free interaction analysis generate unique data on molecular interactions, giving insights into biological functions and disease mechanisms, and facilitating efficient therapeutic development. Application areas include drug discovery, general life science research, antibody characterization, immunogenicity, biotherapeutic development and manufacture. Biacore AB is a GE Healthcare company. Further information: www.biacore.com