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  • Lars Hedbys

    CEO


    Idogen AB Medicon Village Scheelevägen 2 SE 223 81 Lund Sweden
    +46 - 46 - 275 63 30
    http://www.idogen.com
  • Quotes

    For Idogen, it is very pleasing and satisfying to be participating in the establishment of an internationally recognized center for cell- and gene therapy, together with large and small companies in the area, all Swedish universities and several healthcare providers. The collaboration is expected to contribute positively to the development of our tolerogenic vaccines, as it gives us easier and faster access to cell therapy expertise and becomes an important source of support for clinical development and production, logistics and commercialization
    Idogen's CEO Lars Hedbys
    Cell- and gene therapy is a future area that provides the opportunity to cure or treat patients who currently lack treatment options, but in the long term also for major public diseases. We have recently seen significant investments internationally in the area, and it is an extremely important signal that Vinnova is now contributing to making Sweden a leader in the field with such an extensive venture. The unique thing in our granted project is that we create a broad collaboration in which academia, healthcare and small as well as large pharmaceutical companies jointly establish an internationally recognized cell and gene therapy center
    Agneta Edberg, Chair of the board of Idogen and board member in the CAMP project.
    We are very grateful and proud to be one of the few chosen in the tough competition for funding from Horizon 2020, SME Instrument. The fact that EU chooses to fund our project is an important confirmation of the potential of our vaccine technology.
    CEO Lars Hedbys comments
    Based on the three significant advances we have achieved in the past year with successful proof-of-concept in a model of hemophilia, results showing that we can influence parts of the human immune system in test tube experiments and our initiated transfer of the method to a GMP-customed process, we have great confidence in our technology. We have therefore decided on a more progressive development program with parallel development of tolerogenic vaccines within two different important therapeutic areas with need for a novel treatment regimen
    CEO Lars Hedbys
    I look forward to working with Idogen and hemophilia again – a patient group I’ve worked a lot with. Idogen has an interesting technology which can change the current treatment modality of medically very vulnerable patients and I think my previous experiences will be useful.
    Steven Glazer, CMO Idogen
    The granted patent in Europe is a significant endorsement. Idogen develops tolerogenic vaccines with high medical and commercial potential, and we have now secured patent protection for these methodologies in two major markets – Europe and Japan. We also have a Notice of Allowance issued in the USA
    CEO Lars Hedbys
    This patent provides very important protection for our tolerogenic vaccine platform in the USA. This is a key market representing 40% of the global pharmaceutical market and is important territory for innovative therapies such as ours. The decision that the USPTO will grant a patent gives us great encouragement
    CEO Lars Hedbys
    The granting of our patent application in Japan is pleasing and a statement representing a considerable strengthening of Idogen’s patent portfolio
    CEO Lars Hedbys
    This patent provides very important protection for our tolerogenic vaccine platform on the European market – a key market for us. The decision that the European Patent Office intends to grant the patent is very pleasing
    CEO Lars Hedbys
    As another major market for our tolerogenic vaccine is now added to the patent portfolio, our future prospects are strengthened. The decision represents a clear increase in the value of our product portfolio.
    CEO Lars Hedbys
    Big pharma companies have demonstrated interest in cell therapy and keep themselves updated on progress. To out-license part of the portfolio is a clear long-term strategy for Idogen.
    Neil Thomas, CBO in Idogen AB
    The successful proof-of-concept-study in human cells, together with the recent timely financing event, we are now taking another step toward being able to produce our tolerogenic vaccine. Having the agreement ready for GMP synthesis of zebularine means that we are adhering to the communicated schedule for the development toward clinical trials and treatment of patients with severe hemophilia A and antibodies to factor VIII
    Lars Hedbys, CEO Idogen AB
    The study shows that two of the follow-up molecules to Zebularine we have tested so far have a good treatment effect in a model of rheumatoid arthritis, which is very pleasing. This study confirms that we have interesting alternative candidates for new indications. The results strengthen the company’s platform and create important opportunities in the future to out-license projects in several indications
    CEO Lars Hedbys
    Our success in producing human tolerogenic dendritic cells is of major importance to us. We have previously demonstrated proof-of-concept in an animal model – now we have taken the next step and shown proof-of-concept in a study with human cells in vitro. This progress is an important milestone and means that the company has taken a major step towards a treatment method for patients with severe hemophilia A affected by neutralizing antibodies against their vital factor VIII
    CEO Lars Hedbys
    It is with pleasure that we can report the results of our ”proof-of-concept”-study and conclude that Idogen’s tolerogenic vaccine seems to reduce the occurrence of inhibitory factor VIII-antibodies in an animal model of hemophilia A, which is a great success for us. Interestingly is especially that the effect persists long after treatment
    Lars Hedbys, CEO
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