Rapid, high-fluence multi-pass q-switched laser treatment of tattoos with a transparent perfluorodecalin-infused patch: A pilot study

Wausau, WI (October 20, 2015) – Research conducted by Brian S. Biesman MD, FACS, Michael P. O'Neil PhD, and Cara Costner RN, FNP was selected as Editor’s Choice in the October 2015 issue of Lasers in Surgery and Medicine (LSM).

The manuscript titled, “Rapid, high-fluence multi-pass q-switched laser treatment of tattoos with a transparent perfluorodecalin-infused patch: A pilot study” was published in LSM, the official journal of the American Society for Laser Medicine and Surgery, Inc. (ASLMS).

15 subjects with tattoos were involved in the study (two with two tattoos). One half of each tattoo was randomly assigned laser treatment using the perfluorodecalin (PFD) patch; the other half received conventional laser treatment and served as the control. Treatments were repeated every 4-6 weeks and resulted in 11 of the 17 tattoos treated with the PFD patch showing more rapid clearance and higher subject satisfaction than conventional treatment.

“A pilot study was conducted to investigate laser tattoo removal directly through a transparent silicone patch dressing pre-loaded with perfluorodecalin (PFD). The device, recently cleared by FDA, rapidly absorbs gases in the opaque white layer of micro-cavitation bubbles allowing rapid, multiple laser passes. The results indicate that multi-pass treatment of tattoos with highest tolerated fluence facilitated by a transparent PFD-infused patch clears tattoos more rapidly than conventional methods. The presence of PFD in tissue enhances deep light penetration through optical clearing, allows prompt retreatment, enhances patient and provider satisfaction, and eliminates potentially noxious fumes and debris.” stated Dr. Biesman.

Dr. Brian Biesman is the Director of the Nashville Center for Laser and Facial Surgery where he specializes in cosmetic and reconstructive eyelid surgery.   In addition, Dr. Biesman serves as a Clinical Assistant Professor at Vanderbilt University Medical Center, Nashville, TN where he holds appointments in the divisions of Ophthalmology, Dermatology, and Otolaryngology-Head and Neck Surgery.  He also is a Clinical Associate Professor at The University of Tennessee Health Sciences Center in Memphis, TN.

Dr. Biesman’s current research interests include technology-based cutaneous rejuvenation, novel approaches to noninvasive tissue tightening, transcutaneous and minimally invasive lipolysis, soft tissue volume augmentation for facial rejuvenation, transcutaneous delivery of botulinum toxin, technology-based modification of facial muscles, laser-enhanced drug delivery, home-use lasers and light devices, advances in ablative fractional skin resurfacing, cutaneous  repigmentation, and low level light therapy for photorejuvenation.

Editor’s Choice is an exclusive article published in LSM, the official journal of the ASLMS. To view the complete manuscript, visit: aslms.org/professional/lsmeditorschoice

The American Society for Laser Medicine and Surgery, Inc. (ASLMS) is the largest multi-disciplinary professional organization, dedicated to the development and application of lasers and related technology for health care applications. ASLMS promotes excellence in patient care by advancing biomedical application of lasers and other related technologies worldwide. Currently, ASLMS has over 4,000 members, including physicians and surgeons representing more than 51 specialties, physicists involved in product development, biomedical engineers, biologists, nurses, industry representatives and manufacturers. For more information, visit aslms.org .

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The American Society for Laser Medicine and Surgery is the largest multi-disciplinary professional organization dedicated to the development and application of lasers and related technology for health care applications. Our mission is to promote excellence in patient care by advancing biomedical application of lasers and other related technologies world wide.  Our vision is to be the world’s preeminent resource for biomedical laser and other energy based technologies, research, education, and clinical knowledge. 

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