Risk of heart disease for pregnant with high blood pressure

Women with high blood pressure during pregnancy have an increased risk of high blood pressure even 40 years after maternity, which leads in turn to an increased risk of cardiovascular disease. This has been demonstrated by researchers at Sahlgrenska Academy.

In a recent study, researchers at Sahlgrenska Academy, University of Gothenburg examined 105 women who gave birth in the early 1970s. Half the women had elevated blood pressure during pregnancy, while the other half had a normal pregnancy.

The study shows that women who had elevated blood pressure during pregnancy were more frequently diagnosed with high blood pressure even 35 to 40 years later. The same women showed signs of increased stiffening of the arteries and some deterioration in the blood sugar balance.

"We can see that even a minor increase in blood pressure can be connected to some deterioration in the heart's structure and function in these women. Together, these findings can partly explain the increased risk of cardiovascular disease," says Anna-Clara Collén, who reports the results in her thesis.

In order to maintain a healthy cardiovascular system after the menopause, women who have had high blood pressure during pregnancy should make an effort to regain normal blood pressure after pregnancy.

"This is about being physically active and avoiding overweight, for example. It is also important to have accurate and regular blood pressure check-ups," says Anna-Clara Collén.

The Gothenburg study also shows that the women who reported greater self-perceived stress in recent years had a larger waist circumference than those who reported less stress. A larger waist circumference is associated with an increased risk of cardiovascular disease.

The thesis Hypertension and cardiovascular risk factors in women – a follow-up study forty years after hypertensive pregnancies will be the subject of a doctoral disputation on 25 April, 2013.

Link to thesis: https://gupea.ub.gu.se/handle/2077/32005

FACTS ABOUT THE STUDY
In order to understand the mechanism behind why women with raised blood pressure in pregnancy have an increased risk of future cardiovascular disease, the researchers examined the women's blood pressure and pulse, structure and function of the heart and blood vessels, weight and waist circumference and sugar, hormone and salt balance. The women's self-perceived stress was also logged, as well as, in a smaller section of the study population, activity in the sympathetic nervous system.

Contact :
Anna-Clara Collén, Institute of Medicine, Sahlgrenska Academy, University of Gothenburg and specialists at the Clinic of Medicine, Sahlgrenska University Hospital Östra.
anna-clara.collen@vgregion.se
+46708-710 420
+4631-343 52 69

Tutor : Karin Manhem, Senior Lecturer and Chief Physician, karin.manhem@vgregion.se , +46709-310 568

Press Officer
Krister Svahn

Sahlgrenska Academy, University of Gothenburg
46766-18 38 69
4631-786 3869
krister.svahn@sahlgrenska.gu.se


The Sahlgrenska Academy is the faculty of health sciences at the University of Gothenburg. Education and research are conducted within the fields of pharmacy, medicine, odontology and health care sciences. About 4,000 undergraduate students and 1,200 postgraduate students are enrolled at Sahlgrenska Academy. Around 1,400 people work at the Sahlgrenska Academy, 850 of them are researchers and/or teachers. 2012 Sahlgrenska Academy had a turnover of 2,300 million SEK.

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The Sahlgrenska Academy is the faculty of health sciences at the University of Gothenburg. Education and research are conducted within the fields of pharmacy, medicine, odontology and health care sciences. 6,000 students are enrolled at Sahlgrenska Academy and around 1,000 researchers and teachers work at the faculty. www.sahlgrenska.gu.se/english

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