Disturbances in blood cell gene transcription may lead to leukemia
Researchers have succeeded in shedding light on the pathogenesis of DNA breakpoints that are associated with leukemia. A mechanism discovered in a recent study can explain up to 90% of DNA damages present in the most common type of leukemia in children. The study was carried out by the University of Eastern Finland and the University of Tampere, and the findings were published in eLife. Leukemia is the most common form of cancer in children. Thanks to several genome-wide studies carried out over the past years, our understanding of the biology of leukemia has increased rapidly. The fact