UTA enzyme research opens doors to developing new inhibitors for arthritis
Biologists at The University of Texas at Arlington have demonstrated that removing water molecules can deactivate caspase-3 enzymes, which opens new doors for treatment of autoimmune diseases like arthritis, which have been linked to overactive enzymes. Caspase enzymes have important functions in cell development and cell death. Imbalances in this enzyme’s activity can cause too many cells to be killed and not enough to be made, which is the case for arthritis and diabetes. Currently, the activity level required for cell death is undefined, which means that regulating these enzymes