Elypta’s urine test shows game-changing potential in kidney cancer follow-up
Stockholm – March 24, 2025 – Elypta, the Swedish company pioneering metabolism-based cancer diagnostics, is proud to announce that findings from the international AURORAX-0087A (AUR87A) study, the largest diagnostics study ever conducted on the most common type of kidney cancer, were presented today in a Plenary Game Changer Session at the 2025 European Association of Urology Congress.
The AUR87A study, conducted across 29 hospitals in the UK, EU, USA, and Canada, evaluates the use of glycosaminoglycans (GAGomes) as urine-derived metabolic biomarkers to monitor kidney cancer recurrence in patients following surgery.
The intermediary results show that the test correctly identified 90% of patients with recurrent cancer. Notably, a negative score corresponded to a 97% probability of being recurrence-free.
This high negative predictive value supports Elypta’s belief that post-treatment monitoring of cancer patients needs to be transformed. Instead of undergoing repeated radiological exams – a process that can both expose the patient to radiation and constitute a significant burden – patients could submit a simple urine sample.
“These findings show the potentially transformative impact a urine-based test may have in the surveillance of recurrent disease for kidney cancer patients,” says Karl Bergman, Elypta CEO.
“A urine test can offer a less invasive and more comfortable alternative for post-operative monitoring, potentially transforming kidney cancer follow-up care,” said Volker Liebenberg, Chief Medical Officer at Elypta.
While the test is currently designated for research use only, this encouraging data from the AUR87A study underscores its potential to enhance patient care and streamline clinical protocols.
The study’s second patient cohort is nearing final recruitment, with validation results expected later this year.
For more information, please contact:
Karl Bergman, CEO, info@elypta.com
Barnaby Pickering, Media Contact, Barnaby@rhacomms.eu
About AURORAX-0087A
AURORAX-0087A is a prospective multi-center observational in vitro diagnostics clinical validation cohort study to validate the diagnostic performance of GAGome-based tests for the early detection of recurrence after curative intent surgery in patients with high or intermediate risk of clear cell Renal Cell Carcinoma (ccRCC),the most common form of kidney cancer.
The study is registered at www.clinicaltrials.gov where more information is available (https://clinicaltrials.gov/ct2/show/NCT04006405). The study is co-funded by the European Union’s Horizon 2020 research and innovation program under grant agreement No 849251.
About Elypta
Elypta is a Swedish cancer detection company focused on reducing cancer mortality by enabling earlier detection and closer monitoring. The metabolism-based liquid biopsy platform measures a novel panel of glycosaminoglycan biomarkers (GAGome) and algorithms trained to detect cancer-specific signatures. Elypta is advancing a broad study program across different cancers with the leading indications being early detection of recurrence in renal cell carcinoma and multi-cancer early detection. www.elypta.com
