Patent for SAIK-MS approved in the USA

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Patent for SAIK-MS approved in the USA Active Biotech has received patent approval for a group of chemical substances containing candidate drugs against autoimmune and inflammatory diseases. The application in the USA was presented in April 1999 and the product and use patent has now been approved with a patent life of 20 years, valid until 2019. International patent applications were also applied for during 1999 and are pending. One of these substances is being investigated in an ongoing extended phase I clinical trial which also includes patients with the disease multiple sclerosis, MS. SAIK-MS is expected to go into phase II trial during Q4 2000. SAIK is the Active Biotech name for the research project where these types of substances for the regulation of the human immune system are being studied. Two further patent applications are pending regarding candidate drugs for use in other autoimmune and inflammatory diseases, such as juvenile diabetes, rheumatoid arthritis and asthma. The aim is to develop new drugs with improved effectiveness, fewer side effects and in tablet form instead of injection. Lund 29 February 2000 Active Biotech AB (publ) Sven Andréasson President & CEO Active Biotech AB is a Swedish biotechnology group focused on the research and development of pharmaceuticals and vaccines; our core competence being our knowledge of the human immune system. We have a high quality project portfolio and considerable financial resources. Important products include our Cholera vaccine, a vaccine against tourist diarrhoea (ETEC), innovative drugs against MS (SAIK) and cancer (TTS). The turnover of Active Biotech was SEK 267 million in 1999. Active Biotech AB Box 724, S-220 07 Lund, Sweden Tel +46 46-19 20 00 Fax +46 46 19 20 50 E-mail info@activebiotech.com ------------------------------------------------------------ Please visit http://www.bit.se for further information The following files are available for download: http://www.bit.se/bitonline/2000/03/02/20000302BIT00170/bit0001.doc http://www.bit.se/bitonline/2000/03/02/20000302BIT00170/bit0002.pdf