Vitamins D3 / K2 – a powerful yet natural combination from Metabolics

Created and manufactured in the UK, the all natural Vitamins D3/K2 by Metabolics provides the optimum combination of two essential nutrients which work together to provide a wide range of health benefits.

Vitamin D3 is required for absorption of calcium from the gut, regulation of calcium levels in the blood and regulation of over 2,000 genes. Vitamin K2 is required to modify proteins that deposit calcium to the bones, directing the circulating calcium into the bones and teeth while preventing calcium deposits in the arteries.

Studies at the University of York and the University of Copenhagen have demonstrated that Vitamin K2 deficiency is linked to decreased bone density and increased fracture risk. They showed that supplementation with Vitamin K2 reduces bone loss and fractures.

Clinical trials conducted at Keio University School of Medicine, Japan demonstrated that Vitamin D3/K2 combination supplementation is more effective in preventing bone loss than either Vitamins alone. In one study, osteoporotic postmenopausal women were given a D3/K2 combination. Bone density among these woman increased by 4.92% compared to 0.13% in those receiving Vitamin K2 only. This was supported by investigations at Osaka Medical College’s Department of Obstetrics and Gynaecology. In postmenopausal women receiving only calcium, lumbar bone density decreased, while those given either D3 or K2 saw slight increases. The greatest increase in bone density was among the women given a combination of Vitamins D3 and K2.

The Cardiovascular Research Institute, Maastricht conducted a three year study of 181 postmenopausal women. One third received a Vitamin D supplement, one third received a Vitamin D3/K2 combination supplement and one third received a placebo. In the Vitamin D and placebo groups, common carotid artery elasticity decreased. In the D3/K2 group elasticity was maintained.

Osteoporosis and atherosclerosis (arterial calcification) are becoming increasingly linked. Philipps-University’s Department of Internal Medicine has noted that patients with osteoporosis frequently exhibit vascular calcification. An explanation for this connection appears to be Vitamin K deficiency.

Because women produce less oestrogen after the menopause, calcium levels in their bones decrease while depositions in the arteries increase. This increases the risk of osteoporosis and cardiovascular disease. A study published in the American Journal of Health System Pharmacy concluded that Vitamin K2 could reduce this risk.

Each capsule of Metabolics Vitamin D3 & K2 contains:

Cellulose - 80 mg

Vitamin K2 (menaquinone 7) - 25 mg

Vitamin D3 - 2 mg

Metabolics Vitamins D3/K2 is available online at £20.24 per 60 capsule pot and £29.94 per 120 capsule pot.

Founded in 1993, Metabolics supplies nutritional supplements to a global client base of practitioners in a wide range of healthcare disciplines. The company has distributors in Europe, Asia and Australia and receives regular orders from 22 countries including Russia and the USA.

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Editorial contacts:

Emma De Maio
Tel: 07921 160 134



Formed in 1993, Metabolics is the UK’s premium quality supplement manufacturer. Popular in the UK, US, Ireland and across Europe, Metabolics also has distributors in Greece, Singapore and Australia. In total, the company receives regular orders from over 20 countries around the world.

Unlike many suppliers who bottle and market products manufactured overseas, Metabolics manufactures its supplements at itsUKfacility which was upgraded in 2011 to comprise state-of-the-art pharmaceutical clean room equipment.

Metabolics is one of very few manufacturers in the world that does not use binders, hidden fillers or flowing agents (machine lubricants) such as magnesium stearate during their production processes. Although these allow manufacturers to produce a low cost product, Metabolics believes that they compromise the quality of the supplement. Similarly, Metabolics only uses the best possible ingredients.

Manufacturing in theUKenables Metabolics to control and maintain their quality standards. The company is a comparatively small-volume manufacturer that manufactures on demand rather than producing large quantities of stock. This means that, as scientific knowledge of nutrition evolves, Metabolics can respond quickly with new product ranges.  This allows them to maintain their commitment to producing products which best reflect the latest scientific research.

Owned and run by original founder, Alison Astill-Smith, Metabolics has a dedicated workforce and enjoys a very low turnover of staff.  The company has ISO:9001 as well as ISO:14001 accreditation.  These standards recognise Metabolics’ quality management system and commitment to a pro-active environmental policy.

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