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  • AstraZeneca PLC Announces Agreement with Cheplapharm for rights to Atacand in 28 European countries completed

AstraZeneca PLC Announces Agreement with Cheplapharm for rights to Atacand in 28 European countries completed

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1 October 2018 07:00 BST

AstraZeneca has completed an agreement with Cheplapharm Arzneimittel GmbH (Cheplapharm) for the commercial rights to Atacand (candesartan cilexetil) and Atacand Plus (fixed-dose combination of candesartan cilexetil and hydrochlorothiazide) in Europe.

Under the terms of the agreement, AstraZeneca has received a payment of $200 million from Cheplapharm. A time-bound payment of $10 million as well as sales-contingent milestones will also be payable. The present value of the upfront and time-bound payments will be reported as Other Operating Income in the company's financial statements in the third quarter of 2018.

AstraZeneca will continue to manufacture and supply Atacand and Atacand Plus under a supply agreement and will continue to commercialise the medicines in all markets where it still holds the rights.

About Atacand

Atacand (candesartan cilexetil) is a selective, AT1 subtype angiotensin II receptor antagonist blocker (ARB) that is indicated for the treatment of hypertension and heart failure. Atacand is also available in Europe as a fixed-dose combination of candesartan cilexetil and hydrochlorothiazide (Atacand Plus). Atacand is indicated for the management of hypertension in adults and children/adolescents, as well as heart failure in adults. Atacand Plus is indicated for the management of hypertension when monotherapy is not sufficiently effective. Atacand was developed in collaboration with Takeda. Each company holds the exclusive rights to the product in certain markets. In other markets, Atacand is co-marketed by both parties.

About AstraZeneca

AstraZeneca is a global, science-led biopharmaceutical company that focuses on the discovery, development and commercialisation of prescription medicines, primarily for the treatment of diseases in three therapy areas - Oncology, Cardiovascular, Renal & Metabolism and Respiratory. AstraZeneca operates in over 100 countries and its innovative medicines are used by millions of patients worldwide.

For more information, please visit www.astrazeneca.com and follow us on Twitter @AstraZeneca.

Media Relations
Karen Birmingham UK/Global +44   203 749 5634
Rob Skelding UK/Global +44   203 749 5821
Matt Kent UK/Global +44   203 749 5906
Gonzalo Viña UK/Global +44   203 749 5916
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Michele Meixell US +1   302 885 2677
Investor Relations
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Henry Wheeler Oncology +44   203 749 5797
Christer Gruvris Cardiovascular; Metabolism +44   203 749 5711
Nick Stone Respiratory; Renal +44   203 749 5716
Josie Afolabi Other +44   203 749 5631
Craig Marks Finance; Fixed Income +44   7881 615 764
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US toll-free +1   866 381 7277

Adrian Kemp

Company Secretary

AstraZeneca PLC

This information is provided by RNS, the news service of the London Stock Exchange. RNS is approved by the Financial Conduct Authority to act as a Primary Information Provider in the United Kingdom. Terms and conditions relating to the use and distribution of this information may apply. For further information, please contact rns@lseg.com or visit www.rns.com.

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