ASTRAZENECA PLC IRREVOCABLE, NON-DISCRETIONARY SHARE REPURCHASE PROGRAMME

REPURCHASE OF SHARES IN ASTRAZENECA PLC 2nd AND 3rd FEBRUARY

Further to the announcement of its irrevocable, non-discretionary share repurchase programme for the period 20 December 2011 to 2 February 2012, AstraZeneca PLC announced that under the terms of that programme it purchased for cancellation 467,081 ordinary shares of AstraZeneca PLC at a price of 3068 pence per share on 1 February 2012. Upon the cancellation of these shares, the number of shares in issue will be 1,282,762,184.

A C N Kemp

Company Secretary

2 February 2012

Further to the announcement of its irrevocable, non-discretionary share repurchase programme for the period 20 December 2011 to 8 February 2012, AstraZeneca PLC announced that under the terms of that programme it purchased for cancellation 480,298 ordinary shares of AstraZeneca PLC at a price of 2984 pence per share on 2 February 2012. Upon the cancellation of these shares, the number of shares in issue will be 1,282,394,320.

A C N Kemp

Company Secretary

3 February 2012

ASTRAZENECA PLC IRREVOCABLE, NON-DISCRETIONARY SHARE REPURCHASE PROGRAMME

AstraZeneca PLC (the “Company”) today announced that, further to the announcement made on 15 December 2011 in relation to an irrevocable, non-discretionary programme with Barclays Bank PLC to purchase ordinary shares on AstraZeneca’s behalf during the period which commenced on 20 December 2011 and was due to end on 2 February 2012, the programme will be extended, in accordance with its terms, by four additional trading days and will end on 8 February 2012.

Any purchases will be made within certain pre-set parameters and in accordance with both the Company’s general authority to repurchase shares and the Listing Rules. The Company intends to cancel any Shares so acquired.

A C N Kemp

Company Secretary

2 February 2012

Tags: