Dealing by Directors Companies Act 1985 Sections 324/329

We hereby inform you that, with effect from 7 April 2005, Marcus Wallenberg, a Director of the Company, is no longer deemed to have an interest in 3,618 AstraZeneca Ordinary Shares of USD0.25 each, held in the name of one of his children who, on 7 April 2005, attained the age of eighteen years. Consequently, Mr Wallenberg’s interest in AstraZeneca Ordinary Shares has reduced to 67,264 shares, which represents approximately 0.004 per cent of the number of shares currently in issue. G H R Musker Company Secretary 7 April 2005