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Holding(s) in Company

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TR-1: Standard form for notification of major holdings
NOTIFICATION OF MAJOR HOLDINGS (to be sent to the relevant issuer and to the FCA in Microsoft Word format if possible)
1a. Identity of the issuer or the underlying issuer of existing shares to which voting rights are attached: ASTRAZENECA PLC
1b. Please indicate if the issuer is a non-UK issuer (please mark with an "X" if appropriate)
Non-UK issuer
2. Reason for the notification (please mark the appropriate box or boxes with an "X")
An acquisition or disposal of voting rights X
An acquisition or disposal of financial instruments
An event changing the breakdown of voting rights
Other (please specify):
3. Details of person subject to the notification obligation
Name Wellington Management Company LLP
City and country of registered office (if applicable) Boston, USA
4. Full name of shareholder(s)  (if different from 3)
Name Bank of New York (Nominees) LtdBBH ISL NOMINEES LTDBNY (OCS) Nominees LimitedBNY Mellon Nominees LimitedGOLDMAN SACHS INTERNATIONALHSBC Global Custody Nominee (UK) LimitedJapan Trustee Services Bank Ltd.JP Morgan Chase Nominees LimitedMellon Nominees (UK) Ltd.Nortrust Nominees LimitedROY Nominees LimitedState Street Nominees LimitedVIDACOS NOMINEES LIMITED
City and country of registered office (if applicable)
5. Date on which the threshold was crossed or reached: 01/10/2019
6. Date on which issuer notified (DD/MM/YYYY): 03/10/2019
7. Total positions of person(s) subject to the notification obligation:
% of voting rights attached to shares(total of 8.A) % of voting rights through financial instruments(total of 8.B.1 + 8.B.2) Total of both in %(8.A + 8.B) Total number of voting rights of issuer
Resulting situation on the date on which threshold was crossed or reached 3.41% 2.47% 5.88% 1,311,894,438
Position of previous notification (if applicable)
8. Notified details of the resulting situation on the date on which the threshold was crossed or reached:
A: Voting rights attached to shares
Class/type of shares ISIN code (if possible) Number of voting rights % of voting rights
Direct(Art 9 of Directive 2004/109/EC) (DTR5.1) Indirect(Art 10 of Directive 2004/109/EC) (DTR5.2.1) Direct(Art 9 of Directive 2004/109/EC) (DTR5.1) Indirect(Art 10 of Directive 2004/109/EC) (DTR5.2.1)
GB0009895292 Ordinary Shares 44,759,495 3.41%
SUBTOTAL 8.A 44,759,495 3.41%
B 1: Financial Instruments according to Art. 13(1)(a) of Directive 2004/109/EC (DTR5.3.1.1 (a))
Type of financial instrument Expiration date Exercise/ Conversion Period Number of voting rights that may be acquired if the instrument is exercised/converted % of voting rights
Depository Receipt 56,705,376 Depository Receipt shares or 28,352,661 votes on a converted basis 2.16%
Depository Receipt 6,875,371 Depository Receipt shares or 3,437,680 votes on a converted basis 0.26%
Equity Call Option 15/01/2021 01/01/1900to15/01/2021 1,137 Equity Call Option shares or 56,850 votes on a converted basis 0.00%
Equity Call Option 15/11/2019 01/01/1900to15/11/2019 476 Equity Call Option shares or 23,800 votes on a converted basis 0.00%
SUBTOTAL 8.B.1 31,870,991 2.43%
B 2: Financial Instruments with similar economic effect according to Art. 13(1)(b) of Directive 2004/109/EC (DTR5.3.1.1 (b))
Type of financial instrument Expiration date Exercise/ Conversion Period Physical or cash settlement Number of voting rights % of voting rights
Equity Swap 31/01/2020 01/02/2019to31/01/2020 Cash 183,970 Equity Swap shares or 91,985 votes on a converted basis 0.01%
Equity Swap 29/05/2020 04/06/2019to29/05/2020 Cash 140,896 Equity Swap shares or 70,448 votes on a converted basis 0.01%
Equity Swap 31/03/2020 01/04/2019to31/03/2020 Cash 128,263 Equity Swap shares or 64,131 votes on a converted basis 0.00%
Equity Swap 30/04/2020 12/04/2019to30/04/2020 Cash 69,549 Equity Swap shares or 34,774 votes on a converted basis 0.00%
Equity Swap 30/06/2020 02/07/2019to30/06/2020 Cash 56,143 Equity Swap shares or 28,071 votes on a converted basis 0.00%
Equity Swap 31/08/2020 08/08/2019to31/08/2020 Cash 42,723 Equity Swap shares or 21,361 votes on a converted basis 0.00%
Equity Swap 15/05/2020 09/08/2018to15/05/2020 Cash 19,846 Equity Swap shares or 19,846 votes on a converted basis 0.00%
Equity Swap 20/05/2020 08/10/2018to20/05/2020 Cash 17,989 Equity Swap shares or 17,989 votes on a converted basis 0.00%
Equity Swap 15/05/2020 20/02/2019to15/05/2020 Cash 35,896 Equity Swap shares or 17,948 votes on a converted basis 0.00%
Equity Swap 30/04/2020 15/04/2019to30/04/2020 Cash 30,612 Equity Swap shares or 15,306 votes on a converted basis 0.00%
Equity Swap 30/04/2020 08/04/2019to30/04/2020 Cash 29,511 Equity Swap shares or 14,755 votes on a converted basis 0.00%
Equity Swap 15/05/2020 02/03/2018to15/05/2020 Cash 11,419 Equity Swap shares or 11,419 votes on a converted basis 0.00%
Equity Swap 20/05/2020 05/10/2018to20/05/2020 Cash 11,206 Equity Swap shares or 11,206 votes on a converted basis 0.00%
Index Future 01/10/2019 01/01/1900to01/10/2019 Cash 2,089 Index Future shares or 10,879 votes on a converted basis 0.00%
Equity Swap 15/05/2020 10/10/2017to15/05/2020 Cash 8,928 Equity Swap shares or 8,928 votes on a converted basis 0.00%
Equity Swap 20/05/2020 08/01/2019to20/05/2020 Cash 8,741 Equity Swap shares or 8,741 votes on a converted basis 0.00%
Equity Swap 20/05/2020 25/01/2019to20/05/2020 Cash 7,546 Equity Swap shares or 7,546 votes on a converted basis 0.00%
Equity Swap 20/05/2020 23/08/2019to20/05/2020 Cash 7,195 Equity Swap shares or 7,195 votes on a converted basis 0.00%
Equity Swap 15/05/2020 09/02/2018to15/05/2020 Cash 6,300 Equity Swap shares or 6,300 votes on a converted basis 0.00%
Equity Swap 20/05/2020 15/07/2019to20/05/2020 Cash 6,212 Equity Swap shares or 6,212 votes on a converted basis 0.00%
Equity Swap 20/05/2020 06/07/2018to20/05/2020 Cash 4,635 Equity Swap shares or 4,635 votes on a converted basis 0.00%
Equity Swap 05/05/2020 31/07/2019to05/05/2020 Cash 7,671 Equity Swap shares or 3,835 votes on a converted basis 0.00%
Equity Swap 15/05/2020 02/02/2018to15/05/2020 Cash 3,782 Equity Swap shares or 3,782 votes on a converted basis 0.00%
Equity Swap 20/05/2020 03/07/2018to20/05/2020 Cash 3,496 Equity Swap shares or 3,496 votes on a converted basis 0.00%
Equity Swap 20/05/2020 05/04/2018to20/05/2020 Cash 2,982 Equity Swap shares or 2,982 votes on a converted basis 0.00%
Equity Swap 15/05/2020 02/07/2018to15/05/2020 Cash 2,827 Equity Swap shares or 2,827 votes on a converted basis 0.00%
Equity Swap 15/05/2020 23/10/2017to15/05/2020 Cash 2,779 Equity Swap shares or 2,779 votes on a converted basis 0.00%
Equity Swap 05/05/2020 20/08/2019to05/05/2020 Cash 5,393 Equity Swap shares or 2,696 votes on a converted basis 0.00%
Equity Swap 15/05/2020 16/07/2018to15/05/2020 Cash 2,608 Equity Swap shares or 2,608 votes on a converted basis 0.00%
Equity Swap 20/05/2020 13/07/2018to20/05/2020 Cash 2,503 Equity Swap shares or 2,503 votes on a converted basis 0.00%
Equity Swap 20/05/2020 08/10/2018to20/05/2020 Cash 2,309 Equity Swap shares or 2,309 votes on a converted basis 0.00%
Equity Swap 20/05/2020 23/07/2018to20/05/2020 Cash 2,158 Equity Swap shares or 2,158 votes on a converted basis 0.00%
Equity Swap 15/05/2020 11/06/2018to15/05/2020 Cash 1,367 Equity Swap shares or 1,367 votes on a converted basis 0.00%
Equity Swap 20/05/2020 06/04/2018to20/05/2020 Cash 1,267 Equity Swap shares or 1,267 votes on a converted basis 0.00%
Equity Swap 20/05/2020 14/09/2018to20/05/2020 Cash 1,132 Equity Swap shares or 1,132 votes on a converted basis 0.00%
Equity Swap 20/05/2020 03/08/2018to20/05/2020 Cash 1,034 Equity Swap shares or 1,034 votes on a converted basis 0.00%
Equity Swap 05/05/2020 12/08/2019to05/05/2020 Cash 1,926 Equity Swap shares or 963 votes on a converted basis 0.00%
Equity Swap 15/05/2020 14/06/2019to15/05/2020 Cash 1,593 Equity Swap shares or 796 votes on a converted basis 0.00%
Equity Swap 20/05/2020 19/03/2018to20/05/2020 Cash 773 Equity Swap shares or 773 votes on a converted basis 0.00%
Equity Swap 15/05/2020 16/05/2019to15/05/2020 Cash 1,290 Equity Swap shares or 645 votes on a converted basis 0.00%
Equity Swap 15/05/2020 27/07/2018to15/05/2020 Cash 600 Equity Swap shares or 600 votes on a converted basis 0.00%
Index Future 01/10/2019 01/01/1900to01/10/2019 Cash 96 Index Future shares or 501 votes on a converted basis 0.00%
Equity Swap 05/05/2020 15/08/2019to05/05/2020 Cash 841 Equity Swap shares or 420 votes on a converted basis 0.00%
Equity Swap 05/05/2020 13/08/2019to05/05/2020 Cash 834 Equity Swap shares or 417 votes on a converted basis 0.00%
Equity Swap 05/05/2020 02/08/2019to05/05/2020 Cash 818 Equity Swap shares or 409 votes on a converted basis 0.00%
Equity Swap 15/05/2020 26/07/2019to15/05/2020 Cash 647 Equity Swap shares or 323 votes on a converted basis 0.00%
Equity Swap 20/05/2020 25/06/2018to20/05/2020 Cash 314 Equity Swap shares or 314 votes on a converted basis 0.00%
Equity Swap 20/05/2020 21/05/2018to20/05/2020 Cash 200 Equity Swap shares or 200 votes on a converted basis 0.00%
Equity Swap 15/05/2020 08/11/2018to15/05/2020 Cash 172 Equity Swap shares or 172 votes on a converted basis 0.00%
Equity Swap 20/05/2020 03/10/2019to20/05/2020 Cash 162 Equity Swap shares or 162 votes on a converted basis 0.00%
Equity Swap 05/05/2020 13/09/2019to05/05/2020 Cash 66 Equity Swap shares or 66 votes on a converted basis 0.00%
SUBTOTAL 8.B.2 523,211 0.04%


9. Information in relation to the person subject to the notification obligation (please mark the applicable box with an "X")
Person subject to the notification obligation is not controlled by any natural person or legal entity and does not control any other undertaking(s) holding directly or indirectly an interest in the (underlying) issuer.
Full chain of controlled undertakings through which the voting rights and/or the financial instruments are effectively held starting with the ultimate controlling natural person or legal entity (please add additional rows as necessary) X
Name % of voting rights if it equals or is higher than the notifiable threshold % of voting rights through financial instruments if it equals or is higher than the notifiable threshold Total of both if it equals or is higher than the notifiable threshold
Wellington Management Company LLP 5.88%
10. In case of proxy voting, please identify:
Name of the proxy holder
The number and % of voting rights held
The date until which the voting rights will be held
11. Additional information:
Place of completion London
Date of completion 03/10/2019

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