REPURCHASE OF SHARES IN ASTRAZENECA PLC

AstraZeneca PLC announced that on 30 June 2011, it purchased for cancellation 689,005 ordinary shares of AstraZeneca PLC at a price of 3096 pence per share.

Some of these shares were purchased under the terms of the previously announced irrevocable, non-discretionary share repurchase programme for the period 9 May 2011 to 26 August 2011.

Upon the cancellation of these shares, the number of shares in issue will be 1,366,341,829.

A C N Kemp

Company Secretary

1 July 2011