REPURCHASE OF SHARES IN ASTRAZENECA PLC

Further to the announcement of its irrevocable, non-discretionary share repurchase programme for the period 9 May 2011 to 26 August 2011, AstraZeneca PLC announced that under the terms of that programme it purchased for cancellation 136,691 ordinary shares of AstraZeneca PLC at a price of 3148 pence per share on 4 July 2011. Upon the cancellation of these shares, the number of shares in issue will be 1,366,083,838.

A C N Kemp
Company Secretary
5 July 2011