REPURCHASE OF SHARES IN ASTRAZENECA PLC

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AstraZeneca PLC announced that on 8 September 2011, it purchased for cancellation 573,000 ordinary shares of AstraZeneca PLC at a price of 2845 pence per share. Upon the cancellation of these shares, the number of shares in issue will be 1,340,299,839.

A C N Kemp
Company Secretary
9 September 2011

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