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REPURCHASE OF SHARES IN ASTRAZENECA PLC

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AstraZeneca PLC announced that, on 30 November 2011, it purchased for cancellation 142,211 ordinary shares of AstraZeneca PLC at a price of 2895 pence per share. Upon the cancellation of these shares, the number of shares in issue will be 1,302,938,418.

A C N Kemp
Company Secretary
1 December 2011

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