Total Voting Rights

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2 September 2019 15:00 BST

Transparency Directive

Voting Rights and Capital

The following notification is made in accordance with the UK Financial Conduct Authority's Disclosure and Transparency Rule 5.6.1. As at 31 August 2019 the issued share capital of AstraZeneca PLC with voting rights is 1,311,882,856 ordinary shares of US$0.25. No shares are held in Treasury. Therefore, the total number of voting rights in AstraZeneca PLC is 1,311,882,856.

The above figure for the total number of voting rights may be used by shareholders as the denominator for the calculations by which they will determine if they are required to notify their interest in, or a change to their interest in, AstraZeneca PLC under the UK Financial Conduct Authority's Disclosure and Transparency Rules.

About AstraZeneca

AstraZeneca is a global, science-led biopharmaceutical company that focuses on the discovery, development and commercialisation of prescription medicines, primarily for the treatment of diseases in three therapy areas - Oncology, CVRM and Respiratory. AstraZeneca operates in over 100 countries and its innovative medicines are used by millions of patients worldwide. For more information, please visit astrazeneca.com and follow us on Twitter @AstraZeneca.

Media Relations
Gonzalo Viña +44   203 749 5916
Rob Skelding Oncology +44   203 749 5821
Rebecca Einhorn Oncology +1   301 518 4122
Matt Kent BioPharmaceuticals +44   203 749 5906
Jennifer Hursit Other +44   203 749 5762
Christina Malmberg Hägerstrand Sweden +46 8 552 53 106
Michele Meixell US +1   302 885 2677
Investor Relations
Thomas Kudsk Larsen +44   203 749 5712
Henry Wheeler Oncology +44   203 749 5797
Christer Gruvris BioPharmaceuticals (CV,   metabolism) +44   203 749 5711
Nick Stone BioPharmaceuticals (respiratory,   renal) +44   203 749 5716
Josie Afolabi Other medicines +44   203 749 5631
Craig Marks Finance, fixed income +44   7881 615 764
Jennifer Kretzmann Corporate access, retail investors +44   203 749 5824
US toll-free +1   866 381 72 77

Adrian Kemp
Company Secretary

AstraZeneca PLC

This information is provided by RNS, the news service of the London Stock Exchange. RNS is approved by the Financial Conduct Authority to act as a Primary Information Provider in the United Kingdom. Terms and conditions relating to the use and distribution of this information may apply. For further information, please contact rns@lseg.com or visit www.rns.com.

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