Biacore Announces Senior Management Change

Uppsala, Sweden, November 16, 2004. Biacore International AB (Biacore) (SSE: BCOR) announces today that, with regret, it has accepted the resignation of Paul James, Senior Vice President of Commercial Operations. Paul’s unexpected decision to resign from Biacore is due to personal family reasons. Biacore has initiated the search for a new Senior Vice President of Commercial Operations, a position that combines global responsibility for sales, product management and marketing. The Company anticipates appointing an experienced individual with strong commercial knowledge of the global life science sector to this position in the early part of 2005. Until a new appointment is made Erik Walldén, Biacore’s President and CEO will assume direct responsibility of all of the Company’s commercial operations. Erik Walldén, Biacore’s President and CEO said: “ I would like to thank Paul for his contribution to Biacore, particularly the important role he played in the recent Strategic Business Review and his rebuilding of our sales capability in Europe. Looking ahead, I believe that the recent changes that we have made to the Company’s strategy, management and operational structure have put us in an excellent position to move forward. I am confident that with the strong team that we already have in place, allied to the planned recruitment of a new senior commercial professional, we will achieve our goals of returning to profitability in 2005.” - Ends -