BIOHIT OYJ EXPANDS ITS SERVICE LABORATORY OFFERING WITH ACETALDEHYDE DETERMINATIONS

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Biohit now offers determination services for carcinogenic acetaldehyde to the
food and drink industry, among others. 
Biohit's diagnostics business specialises in safe and cost-effective diagnostic 
systems for diseases of the digestive tract. The company has also brought to    
market acetaldehyde binding medical products to reduce the risk of cancers of   
the upper gastrointestinal tract. These products have been developed in         
cooperation with the scientific community.                                      

Biohit has now expanded this business, investing in both technology and         
expertise, so that the carcinogenic acetaldehyde contained in, for example,     
foodstuffs and alcoholic beverages can be measured. Companies in the food and   
drink industry will now be able to send product samples to Biohit for analysis, 
thereby enabling them to offer safer products to their customers. Biohit        
believes that its assay services will also be used by a variety of research     
institutions, supervisory authorities and possibly even consumers. Guidelines   
for sending samples are available at:                                           
www.biohit.com/diagnostics/determination-of-acetaldehyde.                       

In addition to its assay services, Biohit is also commercialising its BioFood   
innovation. BioFood can significantly reduce - or even completely remove - the  
acetaldehyde contained in, for example, beer, wine, strong alcoholic beverages  
and yoghurts. BioFood's core target customer group comprises companies in the   
food and drink industry. For such companies BioFood, when used in conjunction   
with Biohit's assay services, will open up new avenues for product development. 

The health risks associated with acetaldehyde reached the public eye in October 
2009, when the World Health Organisation's International Agency for Research on 
Cancer (WHO, IARC) classed the acetaldehyde contained in or endogenously        
produced from alcoholic beverages as a Class 1 carcinogen, that is, a substance 
that causes cancer in humans (www.biohit.com). Since the WHO's verdict,         
acetaldehyde has been in the same hazard class as, for example, asbestos,       
arsenic, benzene, formaldehyde and smoking.                                     

Acetaldehyde exposure is cumulative, and we should therefore attempt to reduce  
it by all possible means. The easiest way is to quit smoking and reduce alcohol 
consumption. Exposure can also be reduced by consuming alcoholic beverages that 
contain as little acetaldehyde as possible in additive form. Alcoholic beverages
with acetaldehyde concentrations of almost zero are already available. It can,  
however, be difficult for consumers to make right choices, as there are also    
alcoholic beverages whose acetaldehyde concentrations are up to 500 times over  
the safe limit.                                                                 

Choosing beverages and foodstuffs that do not contain any alcohol and/or        
acetaldehyde whatsoever can also significantly reduce acetaldehyde exposure.    
Drinking habits and good dental hygiene can also influence your personal        
exposure to acetaldehyde.                                                       

The risk of acetaldehyde exposure is fairly widespread. This is evident in a    
recent study conducted at Biohit's service laboratory. The acetaldehyde volume  
of three out of fifteen medium-strength brands of beer exceeded permitted levels
(over 100 µmol /l), and three brands also had an acetaldehyde volume that was   
significantly over the risk threshold. The other brands studied also contained  
acetaldehyde, but in concentrations under the risk threshold (40 µmol /l).      

Foodstuffs may contain large amounts of acetaldehyde                            

Foodstuffs are the primary source of acetaldehyde exposure for non-smokers,     
non-drinkers and those who use alcohol in moderation. Acetaldehyde is used in   
flavourings and may either be present as an additive or generated during the    
production process itself.                                                      

Beverages containing over 2.8 per cent ethanol are classed as alcoholic         
beverages. Foodstuffs and so-called non-alcoholic beverages can contain 1-2 per 
cent alcohol and free acetaldehyde in concentrations of up to 3,000 µmol/l      
(home-brewed beer, for example). They expose the mucosa of the upper            
gastrointestinal tract to acetaldehyde through practically identical mechanisms 
as alcoholic beverages.                                                         

More information on acetaldehyde exposure and detailed guidelines are available 
on our website:                                                                 
www.biohit.com/diagnostics/determination-of-acetaldehyde                        
www.biohit.com/acetium                                                          


For more information, contact:                                                  

Jussi Heiniö, President & CEO                                                   
Email: jussi.heinio@biohit.com                                                  
Tel: +358 (0)9 773 861                                                          
                                                
Mikko Salaspuro, MD, PhD, Professor Emeritus                                    
Biomedicum Helsinki, University of Helsinki                                     
Biohit Oyj's scientific advisor                                                 
and Member of the Board                                                         
Email: mikko.salaspuro@helsinki.fi                                              
Tel: +358(0)500 511 689                                                         


Biohit Oyj is a Finnish biotechnology company that was established by Professor 
Osmo Suovaniemi in 1988 and was listed on the Helsinki exchange in 1999 (NASDAQ 
OMX Helsinki). The company takes a focused, long-term approach and applies an   
aggressive innovation and patenting strategy. This strategy was both developed  
and successfully used by Suovaniemi. By the mid-1980s, the two companies he had 
founded in the 1970s - Labsystems Oyj and the joint venture Eflab Oy - were the 
fastest growing and largest companies in the industry in Finland (http://       
www.google.com / search for ”Osmo Suovaniemi vertical measurement principle”).  
                                                                                
Biohit works with scientific communities to generate research results that can  
be used as the basis for new technologies, products and services. Biohit's      
innovations seek to enhance the safety and cost-effectiveness of liquid handling
in laboratories, and also to promote the prevention and early diagnosis of      
diseases of the gastrointestinal tract.                                         

Biohit operates in two business areas: liquid handling and diagnostics. The     
company's liquid handling range includes electronic and mechanical pipettes,    
disposable tips, and pipette calibration and maintenance services for research  
institutions, healthcare and industrial laboratories. Biohit's diagnostics      
business produces products and analysis systems for the early diagnosis of      
diseases of the gastrointestinal tract. These include the GastroPanel           
examination to diagnose diseases of the stomach and their associated risks,     
quick tests for lactose intolerance and Helicobacter pylori infection, and the  
ColonView examination for the early detection of intestinal bleeding            
(www.biohit.com/diagnostics).                                                   

The GastroPanel and ColonView tests yield a great deal of information and are   
recommended for the primary examination of patients presenting dyspepsia        
complaints (such as indigestion and pain or discomfort in the upper abdomen)    
(www.biohit.com/diagnostics). Before these tests were available, self-care with 
pharmaceuticals or yoghurts could delay the diagnosis of treatable cancers,     
including gastric and colorectal cancer, until they were incurable.             

The diagnostics business's goal is to prevent diseases of the gastrointestinal  
tract. In line with this strategy, Biohit has developed the Acetium capsule to  
remove carcinogenic acetaldehyde from the stomach. Acetium is available from    
pharmacies in Finland without prescription.