A special juice coudl be the answer to DVT

Hi there I am sure that you have read and heard the news about the new NICE guidelines for DVT in hospitals. According to doctors, prevention is straightforward, involving leg compression stockings plus a small shot of a blood thinning drug for those at high risk. Patients could also use a natural product called Sirco to help them. Please find press release below about this natural product. Please contact us on 020 7434 4100 if you want any images or try the product for your self. Kind regards Johnny Steyn CCD Public Relations 020 7434 4100

A Special Fruit Juice Could be the Answer to DVT Deep Vein Thrombosis (DVT), is becoming increasingly common with the growth of long haul flights combined with the trend towards a more sedentary lifestyle and less exercise. A 100% pure fruit juice has just been proven to “help maintain normal platelet aggregation, which contributes to healthy blood flow” according to the European Food Safety Authority (ESFA). The fruit juice, called Sirco™, contains Fruitflow®, a special extract of tomatoes, and can now claim, under patent (EP 2035027), that it “influences plasma clotting times thereby implying potential mediation of clotting factors … and will (therefore) be useful in inhibiting the initiation of venous thrombosis and the formation of fibrin clots (DVT).” Eric Bates of Multiple Marketing, the manufacturers of Sirco™ says “Sirco is now proven to have a beneficial effect on blood platelets, reducing the incidence of DVT which can form when you have been stationary for a length of time. If blood clots travel along the venal system they can be very dangerous.” If blood platelets become ‘spiky’, they are much more likely to clump together, forming clots (thrombosis), which can cause high blood pressure, strokes and heart attacks. Fruitflow® works like aspirin, by dampening signals that cause platelets to become spiky (platelet aggregation), preventing clots forming. However, it doesn’t have any of the associated side effects of aspirin, such as internal bleeding and the effects of Sirco™ are apparent within approximately 1½ hours from drinking the first 250ml glass which can last up to 18 hours. Making it perfect for daily use or prior to a flight or long journey. Sirco™ is the only product currently available that contains Fruitflow®, which has recently demonstrated advantages over low-dose aspirin as a natural alternative to thinning the blood, without side effects*. Further trials on the direct effect of Fruitflow® on DVT are due to be carried out in 2010. Sirco™ is available in major retailers such as Waitrose, Holland & Barrett, Ocado and Independent Health food stores, Tree of Life, The Health Store and The Natural Health Company. It is currently available in 1-litre cartons retailing from £1.89p. However in April, a 250ml size, enough for a daily dose of Fruitflow®, will be launched for consumption prior to travelling on journeys from airports or stations. Sirco™ comes in two new delicious 100% pure fruit flavours, Pomegranate & Orange and Blueberry & Apple, both containing Fruitflow®. More information is available from www.sircoheart.com. -Ends- For more information please contact Carolanne Bamford or Justin Clark at CCD Public Relations. T: 020 7434 4100 E: carolanne@ccdpr.com / Justin@ccdpr.com * Fruitflow® vs Aspirin Trial: An ongoing trial by Provexis at the prestigious Rowett Institute of Nutrition & Health, part of the University of Aberdeen, is comparing the effects of both Fruitflow® and aspirin on a single dose basis over a five hour time course. BIOSS performed an independent statistical analysis of the findings. Interim results from the trial show Fruitflow® demonstrated up to 28% reduction from baseline platelet aggregation occurring through three different biological pathways, while aspirin showed up to 60% reduction in one of these pathways, but no effect on the other two. Notes to Editors: • Sirco does not contain artificial sweeteners, preservatives, colours or flavours and is naturally cholesterol and salt free. • One 250ml serving of Sirco contains 3g of Fruitflow® (the recommended daily consumption) and lasts up to 18 hours. • Sirco is a one-a-day drink, which works with your body on the day you drink it. • A 250ml serving of Sirco provides you with one portion of your recommended five fruits a day. • As Sirco is designed for adults it is not recommended for children. • There is no evidence that drinking more than the recommended dose of Sirco, as with eating too many tomatoes, would be harmful. • Tomatoes are proven to contain ingredients with potent antiplatelet properties that help keep blood platelets smooth so they don’t clump together, and so blood flows more freely. Fruitflow® Antiplatelet therapy has become a widely accepted therapeutic intervention to reduce the rate of coronary events and stroke in specific patient groups. However for patients at lower coronary risk, there is still much debate around the impact of undesirable effects vs benefits for recommending the use of antiplatelet therapies such as aspirin.8 As would be expected for a heart health drink, no side effects have been reported in trials to date.2, 3 Sirco has also shown no effect on the natural clotting process which occurs with injury.2, 3 In 2001, having already published data that showed tomatoes contain ingredients with potent antiplatelet properties,4, 5 a team of scientists led by Professor Asim Duttaroy at the Rowett Institute of Health & Nutrition, University of Aberdeen formulated an extract of ripe tomatoes which delivered these effects in vivo. Four years of further clinical research by Provexis have shown that the extract, Fruitflow®, has multiple modes of action in vitro and in vivo, and works against a range of physiological mediators of platelet aggregation including collagen, thrombin, ADP and arachidonic acid.2, 3 Platelet function in response to ADP or collagen was altered in 97% of trial subjects after consumption of Fruitflow®.2, 3 While the average response in studies was in the range 8-23% inhibition of baseline platelet aggregation, a subset of subjects showed a higher response (in the range 20-35% inhibition).2, 3 These individuals had higher than average plasma concentrations of two emerging markers of cardiovascular risk: C-reactive protein and homocysteine, both of which have been reported to affect platelet function.6, 7 It would appear, therefore, that the individuals who show the greatest response are those who could potentially derive greater benefit from a dietary antiplatelet agent. References : 1. O'Kennedy N, Crosbie L, van Lieshout M et al. Data on file. 2. O'Kennedy N, Crosbie L, Whelan S et al. Data on file. 3. Dutta-Roy AK, Crosbie L and Gordon MJ (2001). Platelets 12: 218-227. 4. Antithrombotic agents. EU patent 9920968.7. 5. Cattaneo M. Thromb Haemost 1999; 81: 165-176. 6. Aukrust P et al. Heart 2001; 86: 605-606. 7. Elwood p et al. BMJ 2005;330; 1440 -1443.