Positive Phase II study shows similar clinical outcomes of immunotherapy and antibiotic treatment for recurrent acute cystitis, potentially reducing the need for antibiotics
Hamlet BioPharma - the pharmaceutical company with a strong portfolio of projects for the treatment of cancer and infections - has successfully completed a controlled Phase II clinical trial in patients with recurrent acute cystitis (severe repeated infections of the urinary tract). The company now announces the outcome of a randomized Phase II study where patients were allocated to antibiotic treatment or anakinra, which is an Interleukin1 (IL-1) receptor antagonist (IL-1RA). The results show that most of the patients respond positively to the treatments and that the two treatments,