Activation of the Immune Defence in the Nobel Prize Focus
The 2018 Nobel Prize in Physiology or Medicine awarded jointly to Dr. James P. Allison and Dr. Tasuku Honjo, highlights the significance of the immune system research. ISR is a company developing new immune stimulating pharmaceutical treatments of HIV, tuberculosis and cancer, with the help of the immune system.Our lead substance ISR048 stimulates two of the three pathways leading to T-cell activation, which can be further amplified and extended by adding pharmaceuticals inhibiting CTLA-4 and PD-1 (i.e. Checkpoint Blockage), the subjects of this year’s Nobel Prize. A phase II clinical trial