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We are grateful for this capital injection that enables us to get necessary and crucial results that will be decisive for Oncorena’s continued clinical development of orellanine and new ventures in the field of kidney cancer. We also hope that the results from the upcoming clinical study will be of great benefit to patients in the future
Lars Grundemar, CEO Oncorena AB
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Oncorena’s First Patient Treated with ONC175 (orellanine) in clinial phase I/II trial in Patients with Metastatic Renal Cancer and Dialysis at Karolinska University Hospital in Stockholm, Sweden

LUND, SWEDEN, September 4, 2023 – Oncorena announces first patient treated in the Phase I/II trial of the first-in-class compound, ONC175 (orellanine), in patients with metastatic renal cancer and dialysis. The first treatment was conducted on August 8 without any complication at the Center for Clincal Cancer studies at Karolinska University Hospital, Stockholm, Sweden. The study examines safety, tolerability, pharmacokinetics and antitumor effect when treated with ONC175. ”I am happy to announce first patient, first treatement in our clinical phase I/II trial, Oncorella-1, with ONC175 (

Börje Haraldsson appointed CEO of Oncorena AB

LUND, SWEDEN, June 20, 2022 – Oncorena AB, which is developing a new and potentially groundbreaking treatment for patients with advanced kidney cancer, announces that the Board of Directors of Oncorena AB has appointed Professor Börje Haraldsson as CEO of the company, effective as of today. He thus succeeds Dr. Lars Grundemar, who will leave the company.Professor Börje Haraldsson (MD, PhD, FASN, FAST) is one of the founders of Oncorena. He has played a crucial role in the development of Oncorena's drug candidate orellanine and is considered a world leader in clinical and experimental renal

Oncorena Initiates the Phase I-II Clinical Trial with Orellanine in Advanced Kidney Cancer Patients at Karolinska University Hospital in Sweden

LUND, SWEDEN, February 1, 2022 – Oncorena today announced the initiation of the Phase I-II clinical trial of the first-in-class compound orellanine in patients with advanced kidney cancer on dialysis. The company is dedicated to developing a unique and potential breakthrough therapy for advanced kidney cancer.The drug candidate orellanine, which has an unique mode of action, is being developed for organ-specific chemotherapy with curative potential for patients with advanced kidney cancer undergoing dialysis due to kidney failure. Preclinical evidence shows that orellanine specifically

Oncorena Secures Financing of the Company’s Continued Development of Orellanine, a Potential Breakthrough Therapy for Advanced Renal Cancer

LUND, SWEDEN, December 23, 2021 - Oncorena, developing a potential breakthrough therapy for advanced renal cancer, receives a capital injection of MSEK 66 from one of the company’s principal shareholders together with two new investors. Under the terms of the agreement, Oncorena can receive an additional SEK 94 million in the future. The capital will primarily fund Oncorena's first clinical study, a phase I/II study with orellanine in patients with advanced kidney cancer undergoing dialysis. The current shareholder HealthCap has together with the two new investors, Linc AB and Fåhraeus

Oncorena Receives Approval of First in Patient Trial with Orellanine as a Potential Breakthrough Therapy in Metastatic Renal Cancer Patients

LUND, SWEDEN, March 1, 2021 - Oncorena, dedicated to developing a unique and potential breakthrough therapy for metastatic renal cancer, today announces the Swedish Medical Products Agency’s approval of the Phase 1/2 of First in Patient trial of the first-in-class compound, orellanine in patients with metastatic renal cancer in dialysis.Preclinical evidence shows that orellanine, a well known fungus toxin, specifically exerts powerful anti-tumor effects on metastatic renal cancer in different preclinical models. Orellanine has a unique mode of action. All preclinical activities have been

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