Year-end report 2023/24

FEBRUARY 2024 – APRIL 2024

MAY 2023 – APRIL 2024

IN SHORT

• PHI has increased its recognition in the growing regenerative medicine field. Our CSO, Kersti Alm, delivered an impactful presentation at the Alliance for Regenerative Medicine conference in Rome.
• We welcomed Ivan Jurkovic to the PHI Board to support our growth and strategic objectives.
• In March, PHI’s sales partner, Altium, hired a distributor manager who has been actively engaging with potential sales partners to open new markets and increase our global footprint.
• We have been intensely involved in supporting Altium by training new sales colleagues and providing support at initial product demonstrations, taking noticeable resources from the PHI team. However, we know that we set ourselves up for future returns.
• PHI published “Shaping the Future of Regenerative Medicine – PHI’s Vision for QPI in Cell Therapy Manufacturing” to outline its vision for QPI technology in regenerative medicine and the technology’s capability to enhance cell quality control throughout the whole cell manufacturing cycle – from bedside to bedside.

CEO COMMENTARY

This spring has been a dynamic and productive period for PHI, as our team and partners have made significant efforts on multiple fronts. Externally, our collaboration with Altium has focused on expanding our sales processes and networks and enhancing our market presence. Internally, our dedicated team has been advancing our ongoing regenerative medicine projects and refining our HoloMonitor technology.

Increased Visibility within Regenerative Medicine

Our visibility in the industry has grown substantially through participation in key investor and regenerative medicine events this spring. Our Chief Scientific Officer, Kersti Alm, delivered an impactful presentation at the Alliance for Regenerative Medicine conference in Rome, highlighting our position in the emerging field of regenerative medicine. These engagements help us find new, exciting partnerships and strengthen existing relationships and PHI’s position in the field.

Additionally, we published a well-received opinion piece, “Shaping the Future of Regenerative Medicine – PHI’s Vision for QPI in Cell Therapy Manufacturing“, which outlines our vision for establishing Quantitative Phase Imaging (QPI) as the gold standard for cell quality control measurements for cell therapies. This publication underscores our commitment to innovation in regenerative medicine and highlights our strategic goals for the future.

Strengthening Our Team and Board

To support our strategic growth and expand our market presence, we have had key additions to our team and board. Since March, Daniel Soor has joined the Altium team as our new distributor manager. Daniel is actively engaging with potential new sales partners worldwide, with a mission to open new markets and broaden HoloMonitor’s global footprint. His efforts are central to supporting our sales strategy and expanding our reach through Altium’s extensive network.

Additionally, we were pleased to announce Ivan Jurkovic as a new board member. Ivan, Altium’s CFO, brings a wealth of experience in financial strategies and risk management, which will be invaluable as we pursue our growth objectives in regenerative medicine. His understanding of financial strategies will aid our growth and objectives, ensuring we navigate the complexities of the regenerative medicine market effectively.

Sales Strategy and Progress

Our collaboration with Altium is critical to scaling our sales processes and networks. We are fully aware that building these systems and relationships does not happen overnight. The sales cycle in the pre-clinical research market is inherently lengthy, involving multiple partners and often complex decision-making processes. Researchers and academics usually require extended periods to secure funding or grants necessary for purchasing new equipment, which contributes to the extended sales cycles, which typically range from 6 to 12 months.

Currently, we are intensely involved in supporting Altium with the training and development of all our new sales partners and colleagues. This period is very demanding for the entire PHI team as we provide comprehensive training, assist in initial on-site product demonstrations, and offer hands-on support. I am proud of the whole team for its dedication and teamwork in this fast-moving period. We know that these efforts are essential investments to ensure our partners are well-equipped to represent HoloMonitor effectively and drive sales.

While sales this quarter were not as strong as anticipated due to our focus on intense training, process building and hand-overs, we remain optimistic about Altium’s contributions in the latter part of 2024. The groundwork is laid now, and through rigorous training and support, we look forward and expect to yield improved results as we move forward. We are confident that the strategic initiatives we have implemented will begin to show significant returns, enhancing our market presence and driving growth in the latter half of the year.

Looking Ahead

Moving forward, we are committed to anchoring our position in the regenerative medicine market, expanding our collaborations and HoloMonitor’s global reach. Our goal is to make Quantitative Phase Imaging (QPI) a measurement standard for cell quality control, ensuring that future cell therapies are safe, cost-effective, and widely accessible.

I want to thank our whole PHI team, partners, and stakeholders for their unwavering support and belief in our vision.

Have a good summer,

Patrik Eschricht, CEO

ABOUT PHI

Phase Holographic Imaging (PHI), a leading medical technology company, develops and markets its non-invasive time-lapse imaging instruments for studying living cells.

The foundation of PHI’s current commercial HoloMonitor® products is Quantitative Phase Imaging (QPI) technology. This technology brings an innovative approach to real-time cell quality evaluation. It offers a detailed analysis of a large number of cell health and behavior characteristics without harming or influencing living cells and thus differing from conventional measurement methods, which often jeopardize cell integrity.

PHI is actively focusing on developing its business to expand from its current pre-clinical research market to the sizable healthcare industry and the emerging regenerative medicine field.

PHI envisions setting a new benchmark with QPI as a gold standard method for cell quality control, enabling regenerative treatments to advance and making future cell therapies safe, reliable, and economically and universally accessible for patients worldwide.

The addressable market

PHI has been active within the pre-clinical and biomedical cell research market, having established a global presence with HoloMonitor® systems and their scientific validation in both academia and industry, primarily addressing cancer, stem cell and drug development research.

PHI’s HoloMonitor technology is transforming pre-clinical research by providing a foundation for better cell models, which are critical before clinical drug testing. This innovative approach, utilizing Quantitative Phase Imaging (QPI), ensures cells remain unaffected during analysis. Unlike conventional cell measurement methods that often require genetic manipulation or staining with toxic substances, QPI offers a non-invasive alternative that maintains the integrity of cell cultures. This advancement addresses the critical need for accurate, cost-efficient preclinical data to reduce the high failure rates in drug development. With 9 out of 10 drugs failing in clinical trials due to ineffective results or adverse effects, largely stemming from flawed preclinical outcomes, PHI’s technology represents a significant leap forward. By enabling scientists to obtain better data without compromising cell health, HoloMonitor sets a new standard in drug development and basic medical research, aiming for more successful patient outcomes and reduced research expenses.

PHI is strategically prepared to extend its reach into the large clinical market and emerging regenerative medicine field, which presents significant growth opportunities. By striving to achieve Good Manufacturing Practice (GMP) standards and create a company quality management system (QMS), PHI aims to penetrate these markets in the future, where its non-invasive cell analysis solutions can offer critical cell quality control assessment.

Regenerative medicine is a groundbreaking field focused on developing methods to regenerate, repair, or replace damaged cells, tissues, or organs. It integrates biology, chemistry, computer science, and engineering to develop treatments for conditions previously thought untreatable. It has already begun to transform healthcare by offering new hope to patients with conditions like cancer, Parkinson’s disease, diabetes, and deafness, displaying its vast potential to improve and save lives around the globe.

Business model & strategy

PHI markets a competitive combination of sophisticated software and quality hardware, constantly evolving its offerings through in-house development in response to changing market needs. The production of the hardware and accessories is strategically outsourced to specialized subcontractors located in Sweden.

PHI’s business model strategically centers around the HoloMonitor portfolio, designed to meet the specific needs of academia and industry research labs. The company prioritizes direct interactions and live product demonstrations at potential customer facilities, particularly in cell-based research environments. Combined with a digital marketing approach, this sales strategy is essential for demonstrating HoloMonitor’s advantages firsthand, aiming to foster trust and enabling customers to assess its suitability for their unique research needs. The sales process at PHI is designed to align with the detailed and extended decision-making cycles often found within the scientific community. It accounts for the crucial phase of securing grant funding or other financial support for institutions looking to invest in new research equipment. As a result, sales cycles typically span 6 to 12 months.

PHI is actively expanding its global reach within its current core markets, such as North America, Europe, Asia, and Australia, while also exploring new territories. At the heart of this strategic expansion is the partnership with Altium, a major investor and global distributor of PHI. Altium’s engagement has been transformative for PHI’s operations, not only providing substantial financial backing but also significantly enhancing PHI’s market presence through Altium’s well-established sales channels and distribution networks. The joint efforts aim to broaden the geographic reach and adoption of the HoloMonitor system, utilizing targeted demonstrations and deeper market penetration to enhance sales performance and cash flow, positioning PHI as a key player in its field. This collaboration enables PHI to focus on its core expertise and innovation capabilities—advancing QPI technology and product development within regenerative medicine.

Achieving future goals

PHI is focusing on achieving important milestones in the coming years, utilizing the potential of its partnerships and collaborations. PHI has a clear focus on expanding its business to the clinical research market and positioning itself in the Regenerative Medicine field.

The collaboration with Altium is instrumental in PHI’s approach to gaining a stronger foothold in the regenerative medicine field, where PHI’s cell quality control technology can meet critical industry needs. PHI is also actively fostering alliances with leading institutions such as the Wake Forest Institute for Regenerative Medicine (WFIRM), renowned for its groundbreaking contributions to translating scientific research into clinical therapies. Collaborating with WFIRM enriches PHI’s initiatives, providing access to an exceptional ecosystem of expertise and innovation. This partnership bolsters PHI’s leadership in regenerative medicine, enabling the ongoing development and application of PHI’s cell quality control technology.

PHI engages in these strategic relationships to fortify the Company’s position as a thought leader in the field with the intention to accelerate progress, bolster market penetration, open new doors to new business opportunities, and enhance shareholder value.

NET SALES AND RESULTS

Net sales for the third quarter amounted to 1 686 (1 869) KSEK and operating results before depreciation (EBITDA) to -2 719 (-4 240) KSEK. The net result amounted to -5 349 (-7 717) KSEK.

INVESTMENTS

With an emphasis on regenerative medicine, the company invested 2 110 (2 667) KSEK in the product, patent, and application development during the period.

FINANCING

Cash, cash equivalents, and unutilized granted credits amounted to 810 (7 307) KSEK by the end of the period. After closing PHI took a bridge loan in the amount of 7 000 KSEK. The equity ratio was 15 (11) %.

Warrants of series TO 3

On 2 May 2023, the exercise period for warrants of series TO 3 (“TO 3”), which were issued in connection with Phase Holographic Imaging PHI AB’s (“PHI” or the “Company”) rights issue of units that were announced on 22 February 2022, ended. 3 201 739 warrants of series TO 3 were exercised, corresponding to a subscription ratio of approximately 95.1 percent. Thus, the underwriting commitment relating to TO 3, which the Company agreed on during the exercise period, was activated. The decision on a directed share issue of 163 666 shares, corresponding to the remaining approximately 4.9 percent of the warrant exercise, to the underwriter Altium SA (“Altium”) was taken, with the support of the authorization given by the annual general meeting held on 31 October 2022. The proceeds of the TO 3 warrants amount to approximately SEK 12.7 million before the deduction of transaction-related costs, corresponding to a subscription rate of 100 percent.

Warrants of series TO 4

Each warrant of series TO 4 entitles to subscribe for one (1) new share in PHI during the period from and including 12 September 2024 to and including 3 October 2024. The exercise price amounts to 70 % of the volume-weighted average price during a period prior to option redemption, within the interval 0.20 SEK as the lowest, and with 15.45 SEK per new share as the highest exercise price. Upon full exercise of warrants of series TO 4 at the highest exercise price (15.45 SEK per new share), the warrants will provide the company with approximately 20.8 MSEK before issue costs.

Convertibles

The convertible loan to Formue Nord Fokus A/S end of October 2023 amounted to 20 230 000 SEK with the following terms:

• Number of convertibles: 1 700 000 convertibles, which entails the right to subscribe for 1 700 000 new shares.
• Conversion rates: 11.90 SEK per new share until 2 May 2023 (last day in the exercise period for warrants of series TO 3) and 15.45 SEK per new share from May 3, 2023, until October 16, 2024.
• Conversion period: the convertible holder is entitled during the period from the date of payment to October 16, 2024, to convert the loan into shares.
• Maturity: in the event that the entire loan is not converted, repayment of the loan and interest must take place no later than October 16, 2024. The company has the right to repay all or part of the convertible loan at any time until the due date, after which Formue Nord has the opportunity to accept repayment or request conversion according to the above conversion rates.
• Interest: the convertibles run at a quarterly interest rate of 3%.

Altium acquired Formues Convertible loan

In November, Altium acquired the convertibles from Formue Nord A/S. On the takeover day, PHI had repaid 6 360 KSEK on the convertible loan including accumulated interest. The convertible loan net amount that Altium took over amounted to 17 841 KSEK and the number of outstanding convertibles to 1 449 277 new shares.

RISKS

The company may be affected by various factors, described in the 2022/23 Annual Report. These factors may individually or jointly increase risks for the operation and result of the company.

ACCOUNTING PRINCIPLES

The accounts are prepared in accordance with the Annual Accounts Act and general advice from the Swedish Accounting Standards Board BFNAR 2012:1 Annual accounts and consolidated accounts (K3).

REVIEW

This interim report has not been subject to review by the company’s auditor.

STATEMENTS ABOUT THE FUTURE

Statements concerning the company’s business environment and the future in this report reflect the board of director’s current view of future events and financial developments. Forward-looking statements only express the judgments and assumptions made by the board of directors on the day of the report. These statements have been carefully assessed. However, it is brought to the reader’s attention that these statements are associated with uncertainty, like all statements about the future.

CALENDAR

• 16th of September, Interim Report 1 2024/2025
• End of September: Publication of annual report, which will be available in our office in Lund and on www.phiab.com

ABOUT PHI

Phase Holographic Imaging (PHI) is a medical technology company that develops and markets its non-invasive, time-lapse imaging instruments for long-term quantitative analysis of living cells. The foundation of PHI’s current commercial HoloMonitor® products is Quantitative Phase Imaging (QPI) — a technology that heralds an innovative approach to cell quality evaluation. It offers a detailed analysis of cell characteristics without harming the cells, avoiding the limitations of traditional measurement methods. PHI is actively focusing on business development to expand from pre-clinical research to the clinical market and the emerging regenerative medicine field. PHI envisions transforming live cell analysis and establishing QPI as a standard for cell quality control, making our future cell therapies safe, affordable, and accessible for patients. PHI is based in Lund, Sweden, Boston, MA and Winston-Salem, NC.

On behalf of the Board of Directors
Patrik Eschricht, CEO

For additional information, please contact:
Patrik Eschricht
E-mail: ir@phiab.com
Web: www.phiab.com – Live cell imaging & analysis