Research highlight: Dendritic Nanogels (DNGs) show promising results in new study

In a recently published study by Zhang et al, dendritic nanogels (DNGs) show promising results as carriers of antimicrobial peptides (AMP) for topical treatment of skin infections. DNGs were made commercially available by Polymer Factory in December 2022.

The study was conducted with the aim of finding a topical delivery strategy for AMPs, which are promising antibacterial agents. AMPs were encapsulated in DNGs and subsequently embedded in a hydrogel, which formed the delivery system. In-vitro studies showed good biocompatibility and in-vivo models showed superior efficacy of the DNG-encapsulated AMPs compared to the AMP in solution.

The study was published in the journal Macromolecular Bioscience in January 2023. Find the link to the paper here.

Find more information about Polymer Factory’s DNGs here.

*Note: The research that was conducted belonged to Prof. Michael Malkoch at KTH, the Malkoch Group, and was not influenced or sponsored by Polymer Factory. Prof. Malkoch is the CTO of Polymer Factory.

For more information about Polymer Factory, please contact:
Elin Mignérus, CEO
Phone: +46 (0) 79 300 27 76
E-mail: elin.mignerus@polymerfactory.com

Polymer Factory (publ) is a leading global provider and producer of dendritic materials, with customers ranging from BigPharma, MedTech and BioTech companies, to research-intensive institutes and academic research groups. The Company’s dendritic materials act as smart delivery systems that enhance the effects of the substances they carry, e.g. a vaccine or an anticancer drug. They have also shown great promise in diagnostics, tissue engineering and in the development of vaccines. In addition, Polymer Factory has used the Company’s vast knowledge and expertise to develop a patented calibration technology, named SpheriCal®, designed for Mass Spectrometry instruments. The Company’s dendritic nanotechnologies have the potential to accelerate innovation in technologically demanding sectors, such as MedTech and BioTech. Learn more at www.polymerfactory.com.