Shimadzu’s Nexera UHPLC Delivers the Ultimate in LC/MS(/MS) Front End Performance

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COLUMBIA, Md., June 23, 2010 — The new Nexera ultra high-performance liquid chromatography (UHPLC) system builds on Shimadzu’s foundation as the leader in HPLC front ends for mass spectrometry, delivering the speed, resolution and reliability, as well as pulse-free operation, for the most demanding LC/MS(/MS) applications.

Because high-sensitivity analysis of complex samples is necessary, the front-end component for LC/MS(/MS) must decrease its carryover to zero. With a newly designed injection port and fine-tipped needle, along with additional features such as multiple-rinse solvent selection and injection port and internal needle rinse, the Nexera SIL-30AC autosampler reduces carryover to an absolute minimum. The SIL-30AC also features an ultrafast injection speed — just 10 seconds — as well as an overlapping injection function to allow for a maximum reduction in cycle time.

In addition, the LC-30AD pump features an automatic pulsation-correction mechanism and a high-speed parallel micro plunger design to provide pulse-free solvent delivery and excellent retention time reproducibility, even in ultra-high speed gradient conditions. Moreover, a new mixer (MiRC) conceived from the study of micro reactor technologies delivers efficient, low-volume mixing for even the most difficult analysis, thereby minimizing gradient delay.

Nexera’s modular components interact with the precision of an integrated system while allowing users to design and upgrade a system to fit their application requirements.

For more information about Nexera UHPLC, visit www.ssi.shimadzu.com/nexera.

About Shimadzu Scientific Instruments Inc.

Shimadzu Scientific Instruments (SSI) is the American subsidiary of Shimadzu Corporation, headquartered in Kyoto, Japan. Founded in 1875, Shimadzu is a $2 billion multinational corporation with three major divisions: Medical Diagnostics, Aerospace/Industrial and Analytical Instruments. The Analytical Division is one of the world's largest manufacturers of analytical instrumentation and environmental monitoring equipment. In 1975, SSI corporate headquarters was established in Columbia, Md. to provide analytical solutions to laboratories in North, Central and parts of South America. In the U.S., SSI has a network of more than 50 locations providing local and regional sales, service, and technical support.

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Shimadzu Scientific Instruments Inc.
7102 Riverwood Drive
Columbia, MD 21046
www.ssi.shimadzu.com

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