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Athletes' health - effects of environmental pollutants and nutrition on epithelial barrier function and healthy microbes in the body

Novel concepts highlight a holistic approach to overall health and physical performance of athletes (professional sporters and physically active persons), linked with their nutrition and exposure to pollution and toxic substances affecting the integrity of their barriers of skin and mucosal body surfaces and healthy microbiome.Athletes' health - effects of environmental pollutants and nutrition on epithelial barrier function and healthy microbes in the body   The health of athletes and physically active people is in the focus of the current research in the Swiss Institute of Allergy

Novel classification of allergic disorders published by the European Academy of Allergy and Clinical Immunology.

Nomenclature of allergic diseases and hypersensitivity reactions: Adapted to modern needs: An EAACI position paper published in "Allergy"The revision of the current allergic disease nomenclature based on symptoms and organ dysfunction has been long-awaited at the time of modern patient-tailored treatments and precision medicine. The new classification is based on disease mechanisms, thus facilitating targeted and personalised disease management. EAACI is the world leader in allergy science and education. The world’s key opinion leaders gathered around the initiative of the European

Detergents disrupt barrier integrity and induce inflammation in mouse and human skin

A novel approach for rapidly assessing epithelial barrier integrity reveals the negative impact of detergents and sodium lauryl (dodecyl) sulphate on skin health     The results underscore the pressing need to establish a new safety standard for household cleaning products   The Swiss Institute of Allergy and Asthma Research  (SIAF) today announced the findings of a new study demonstrating the mechanisms of skin epithelial barrier impairment caused by household laundry detergents. Published online today in Allergy, Household laundry detergents

New Study Reveals Negative Impact of Common Food Emulsifiers on Gut Health

Polysorbate 20 and Polysorbate 80 were shown to damage the gut barrier, leading to cell death and inflammation –– even at doses 10 to 20 times lower than those currently authorized for use The findings illustrate the urgent need to use fine-scale immunology to evaluate safety and establish a new standard for consumer productsDavos, 2 August 2023   New Study Reveals Negative Impact of Common Food Emulsifiers on Gut Health   Polysorbate 20 and Polysorbate 80 were shown to damage the gut barrier, leading to cell death and inflammation –– even at doses 10 to 20 times lower than

Disrupted epithelial barriers as a predictor of severe COVID-19 development

Severe Covid-19 in epithelial barrier disrupted subjectsDavos, 09 July 2023     Disrupted epithelial barriers as a predictor of severe COVID-19 development   According to the epithelial barrier theory, disruption of epithelial barriers by environmental and toxic agents triggers microbial dysbiosis, bacterial translocation to subepithelial areas and local or systemic immune/inflammatory response to environmental agents, allergens and microbes. Such events have been implicated in the development of chronic conditions like allergic, autoimmune, and metabolic diseases, such as

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