NICE Recommends TEPKINLY[®] ▼ (epcoritamab), a Subcutaneous Bispecific Antibody for Adults With Relapsed/Refractory (R/R) Follicular Lymphoma (FL) After Two or More Lines of Systemic Therapy
· Epcoritamab can now be accessed as a treatment option for adults with follicular lymphoma who have received two or more systemic treatments, only if epcoritamab is stopped after 3 years of treatment or earlier if the lymphoma progresses.[1] · The NICE recommendation is based on the single-arm Phase 1/2 EPCORE NHL-1 trial, where epcoritamab demonstrated responses in people whose cancer has returned or has not responded to at least two treatments.[2] · Follicular lymphoma is an incurable blood cancer that affects around 2,300 people in the UK every year, it is a challenging form