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In the past, resistance mechanisms were usually thought of as static. Our study demonstrates, conversely, that a binary designation of resistance may oversimplify cancer’s true biology. These genetic mutations can fluctuate over time, and some patients can harbor more than one mutation.
Zofia Piotrowska, MD, lead author of the study
In an era where cancer treatment is increasingly personalized to the biology of each individual patient, our findings highlight the importance of molecular testing and the need for improved, noninvasive methods for serial testing.
Zofia Piotrowska, MD
In the past year, the Vice President’s moonshot initiative has brought critical attention to the need for greater collaboration and innovation in cancer research, and we are invigorated at the prospect of radiation oncology being an instrumental component of future progress. Moving forward, we must maintain the focus on advancing both the science and practice of cancer care while aligning our efforts to move Congress to authorize the $700 million requested by the President for cancer research initiatives. Substantial, predictable financial support is essential to sustain the fight to eradicate cancer.
Bruce G. Haffty, MD, FASTRO, past Chair of ASTRO’s Board of Directors
The goal of ASTRO’s 2016 Annual Meeting is to highlight the latest scientific and technological advances while emphasizing the importance of radiation oncology in providing value to cancer patients through cure and palliation.
ASTRO President David C. Beyer, MD, FASTRO
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Genetic profile of treatment-resistant lung cancer more variable than previously understood

Study finds that acquired resistance mechanisms to targeted therapies often changed over time and that some patients demonstrated simultaneous genetic mutationsThe genetic mutations underlying treatment resistance in non-small cell lung cancer (NSCLC) are more complex and dynamic than previously thought. Analysis of 355 biopsied tumors from patients who acquired resistance to EGFR inhibitors, the most common form of targeted therapy for NSCLC, found that mutations frequently varied between biopsies and that nearly one in five patients harbored more than one type of genetic resistance to

CancerLinQ Partners with Premier Radiation Oncology Society

Partnership with American Society for Radiation Oncology Expands CancerLinQ’s Database and Insights to Include Key Cancer SpecialtyCancerLinQ LLC and the American Society for Radiation Oncology (ASTRO) are partnering to bring radiation oncology expertise to CancerLinQ and improve the care of cancer patients nationwide. ASTRO will provide guidance for the development of the CancerLinQ platform to ensure that the system captures more relevant patient data to drive actionable decision-making in cancer care, as well as to advance public policy and population health issues. ASTRO also will use

Cancer researchers to convene for Multidisciplinary Thoracic Cancers Symposium in March

Conference will feature advances in research and clinical care for lung and chest cancersARLINGTON, Va., February 16, 2017 — The 2017 Multidisciplinary Thoracic Cancers Symposium , co-sponsored by the American Society for Radiation Oncology  (ASTRO), the American Society of Clinical Oncology  (ASCO) and The Society of Thoracic Surgeons  (STS), will feature advances in surgery, radiation therapy, chemotherapy and novel molecular biologic therapies for thoracic

Radiation therapy continues to be gold standard for palliative care of painful bone metastases

Updated ASTRO guideline upholds standard of care and emphasizes safety and efficacy of radiation treatmentThe American Society for Radiation Oncology (ASTRO) recently published an updated clinical guideline that underscores the safety and effectiveness of palliative radiation therapy (RT) for treating painful bone metastases. Based on recent clinical trial data, the guideline recommends optimal RT dosing schedules for pain relief, including options for re-treatment. The guideline, “Palliative radiation therapy for bone metastases: Update of an ASTRO Evidence-Based Guideline 

ASTRO urges lawmakers to maintain health care access for vulnerable patients

Medical specialty society outlines principles of patient-centered health care reform and emphasizes importance of protecting patient populationsAs the new Congress and administration wrestle with policy decisions on the provision of high quality, affordable health coverage, the American Society for Radiation Oncology (ASTRO) urges policymakers to prioritize reforms that avoid disruption in coverage and care. Patients fighting cancer should not have to battle for insurance while they battle for their lives. Studies have demonstrated that a lack of health insurance leads to delayed

ASTRO supports nomination of Dr. David Shulkin to lead Department of Veterans Affairs

ARLINGTON, Va., January 24, 2017 – The American Society for Radiation Oncology (ASTRO) today expressed strong support for the nomination of David Shulkin, MD, as Secretary of the Department of Veterans Affairs (VA). ASTRO Chair David C. Beyer, MD, FASTRO, issued the following statement: “ASTRO is deeply committed to improving the quality of cancer care for our nation’s veterans and all Americans. We believe Dr. Shulkin’s experience as VA undersecretary and as a physician-executive makes him uniquely qualified to accelerate reforms that will improve quality in the VA health system. “

D.C.-based medical society’s new HQ garners design awards

Two real estate associations honor ASTRO office for its interiorsARLINGTON, Va., December 15, 2016 – Six months after moving in, the interior design accolades are stacking up for the new headquarters of the American Society for Radiation Oncology  (ASTRO). Earlier this month, the Northern Virginia chapter of NAIOP, the Commercial Real Estate Development Association, presented ASTRO with their Award of Excellence  in the Interiors category of its 2016 design awards. In October, Commercial

ASTRO announces Varian support for radiation oncology safety and quality initiative

ARLINGTON, Va., December 15, 2016 -- The American Society for Radiation Oncology (ASTRO) announced today that Varian Medical Systems has provided significant financial support to RO-ILS: Radiation Oncology Incident Learning System® , a national patient safety initiative launched in 2014  by ASTRO and the American Association of Physicists in Medicine (AAPM). RO-ILS® facilitates safer and higher quality care in radiation oncology by providing a

ASTRO applauds nominations of Tom Price and Seema Verma to top federal health posts

ARLINGTON, Va., November 29, 2016 – The American Society for Radiation Oncology (ASTRO) today expressed its support for the nominations of Tom Price, MD, as Health and Human Services (HHS) Department Secretary and Seema Verma as Centers for Medicare and Medicaid Services (CMS) Administrator. ASTRO Chair David C. Beyer, MD, FASTRO, issued the following statement: “ASTRO congratulates Dr. Tom Price on his nomination to serve as HHS Secretary. We believe Dr. Price's experience and expertise as a physician will be critical in addressing the health care challenges faced by patients and health

Updated ASTRO guideline expands pool of suitable candidates for accelerated partial breast irradiation

Guideline update also examines intraoperative radiation treatment options for early-stage breast cancerThe American Society for Radiation Oncology (ASTRO) today issued an updated clinical practice statement for accelerated partial breast irradiation (APBI) 30184-9/fulltext) for early-stage breast cancer. The updated guideline reflects recent evidence that greater numbers of patients can benefit from accelerated treatment and also provides direction for the use of intraoperative radiation therapy (IORT) for partial breast irradiation. The

ASTRO leadership visits White House to participate in Vice President’s cancer moonshot event

Society continues to encourage inclusion of radiation oncology in strategic planning for the initiative and applauds collaborative efforts with industry and governmentWASHINGTON, D.C., October 18, 2016 – Leadership from the American Society for Radiation Oncology (ASTRO) participated in an event at the White House yesterday hosted by Vice President Joe Biden, who released a report outlining the Cancer Moonshot Initiative’s (CMI) progress to date and roadmap for its four remaining years. Former Chair of ASTRO’s Board of Directors Bruce G. Haffty, MD, FASTRO, attended on behalf of the Society

Radiation Oncology Institute announces winners of innovative research projects in radiation oncology awards

Projects examine how to better manage cancer patient outcomes using smartphone technology and fitness trackersARLINGTON, Va., October 13, 2016 – The Radiation Oncology Institute (ROI) has selected two promising, early career researchers to receive a total of nearly $100,000 for research on how physicians can use the real-time monitoring and feedback capability of smart technologies to improve outcomes for cancer patients. The two winners of ROI’s 2016 Innovative Projects in Radiation Oncology grant awards were recently recognized at the American Society for Radiation Oncology (ASTRO) 58th

ASCO, ASTRO and SSO update guideline on postmastectomy radiotherapy

ALEXANDRIA, Va, ARLINGTON, Va, ROSEMONT, Ill. — Three leading national cancer organizations today issued a joint clinical practice guideline update for physicians treating women with breast cancer who have undergone a mastectomy. The update provides additional considerations for physicians to determine which patients might benefit from postmastectomy radiotherapy (PMRT). “We still don’t have a single, validated formula that can determine who needs PMRT, but we hope that the research evidence summarized in this guideline update will help doctors and patients make more informed decisions,”

ASTRO encourages prostate cancer patients to weigh long-term impact of treatment options with their doctors

ARLINGTON, Va., September 15, 2016 -- In light of the findings from the Prostate Testing for Cancer and Treatment (ProtecT) trial published yesterday in the New England Journal of Medicine, the American Society for Radiation Oncology (ASTRO) would like to congratulate the authors and investigators for conceiving and completing a difficult clinical trial to randomize care for 2,664 men who volunteered to be a part of this study. Their paper emphasizes the importance of joint decision making between prostate cancer patients and their physicians when weighing treatment options for early stage

Clinical trials and emerging research in radiation oncology to be featured at ASTRO’s Annual Meeting in Boston

Press program will highlight innovations in cancer care from 15 leading studies in five news briefings held live on-site and via webcastThe American Society for Radiation Oncology (ASTRO) announced today the press program for its 58th Annual Meeting, which includes multiple reports from phase III clinical trials, researchers from leading institutions in the U.S. and abroad, and examinations of a range of cancer types and patient populations. Researchers will share their findings in a series of briefings held on-site at the Boston Convention & Exhibition Center and webcast to registered

ASTRO awards $275,000 in grants to support early career researchers in radiation oncology

The American Society for Radiation Oncology (ASTRO) has selected four early career scientists to receive a total of $275,000 in research awards, including one winner of the ASTRO Junior Faculty Career Research Training Award and three recipients of ASTRO Resident/Fellows in Radiation Oncology Research Seed Grants. All winners will be recognized at ASTRO’s 58th Annual Meeting, September 25-28, 2016, at the Boston Convention and Exhibition Center. “ASTRO awards and grants support work in the field of radiation and cancer biology, radiation physics and translational research,” said ASTRO

New ASTRO clinical practice statement updates treatment standard for rectal cancer

Recommendations modernize standard trimodal approach with greater customization and propose instances where treatment may be reducedThe American Society for Radiation Oncology (ASTRO) recently issued a new clinical practice statement, “Appropriate Customization of Radiation Therapy for Stage II and III Rectal Cancer: An ASTRO Clinical Practice Statement Using the RAND/UCLA Appropriateness Method.” An executive summary 00413-0/pdf) of the guideline was published in the May-June 2016 issue of Practical Radiation Oncology (PRO), ASTRO’s

Greater Boston area breast cancer survivor, volunteer selected as ASTRO’s 2016 Survivor Circle Award winner

Theresa A. Keresztes will be recognized at ASTRO’s Annual Meeting in BostonThe American Society for Radiation Oncology (ASTRO) has chosen Theresa A. Keresztes, a resident of Wellesley, Massachusetts, to receive the 2016 Survivor Circle Award. Keresztes will be presented with the award, including $1,000, during an awards ceremony at ASTRO’s 58th Annual Meeting, September 25-28, 2016, at the Boston Convention and Exhibition Center. The Survivor Circle Award recognizes a cancer survivor who lives in the region where ASTRO holds its Annual Meeting and has dedicated his or her time and energy

ASTRO members elect five new officers to Board of Directors

President-elect, Secretary/Treasurer-elect, and Vice-chairs of Education, Government Relations and Clinical Affairs and Quality Councils take office in SeptemberMembers of the American Society for Radiation Oncology (ASTRO) have elected five new officers to the Society’s Board of Directors, including President-elect, Secretary-Treasurer-elect, and Vice-chairs of three of ASTRO’s five councils (Clinical Affairs and Quality, Education and Government Relations). Terms for all positions begin at the Annual Business Meeting at ASTRO’s 58th Annual Meeting, to be held September 25-28, 2016 in

ASTRO applauds Senate Finance Committee examination of self-referral law

Radiation oncology society agrees with witnesses urging reforms to loophole for radiation therapy servicesThe Chair of the American Society for Radiation Oncology (ASTRO), Bruce D. Minsky, MD, FASTRO, issued the following statement supporting witness testimony from today’s Senate Finance Committee hearing, “Examining the Stark Law: Current Issues and Opportunities,” during which all three witnesses testified in agreement that changes are needed to the law’s in-office ancillary services (IOAS) exception. ASTRO supports narrowing the IOAS exception to limit inappropriate physician self-

Ten new ASTRO Fellows named in 10th anniversary of FASTRO designation

Ten distinguished members of the American Society for Radiation Oncology (ASTRO) have been named ASTRO Fellows, in the 10th anniversary year that the designation has been awarded. The 2016 class of Fellows will be recognized at an awards ceremony during ASTRO’s 58th Annual Meeting, to be held September 25-28, 2016, in Boston. The ASTRO Fellows designation, or FASTRO, honors individuals who have significantly added to the field of radiation oncology in the areas of research, education, patient care or service and leadership. Designees also have been an active or emeritus member of ASTRO

Brachytherapy pioneer Haakon Ragde, MD, chosen as ASTRO 2016 Honorary Member

The American Society for Radiation Oncology (ASTRO) has selected Haakon Ragde, MD, as its 2016 Honorary Member, the highest honor ASTRO bestows on distinguished cancer researchers, scientists and leaders in disciplines other than radiation oncology, radiobiology or radiation physics. Ragde will be inducted as the 2016 ASTRO Honorary Member during an awards ceremony at ASTRO’s 58th Annual Meeting, September 25-28, 2016, in Boston. The first ASTRO Honorary Membership was awarded in 1989. Ragde is the 33rd physician to be chosen for the honor. “Dr. Ragde is a luminary in the field of

Innovators and leaders in the field of radiation oncology honored with ASTRO Gold Medal awards

Three leaders in radiation oncology, including clinicians and researchers from Duke University, Massachusetts General Hospital and Cedars-Sinai Medical Center, have been named recipients of the American Society for Radiation Oncology (ASTRO) Gold Medal, the highest honor bestowed upon members of the world’s largest radiation oncology society. Benedick A. Fraass, PhD, FASTRO, Christopher G. Willett, MD, FASTRO, and Anthony L. Zietman, MD, FASTRO, will be recognized at an awards ceremony during ASTRO’s 58th Annual Meeting, to be held September 25-28, 2016, in Boston. ASTRO awards its

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