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Asarina Pharma AB (publ) Annual Report 2020 released

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Asarina Pharma CEO Peter Nordkild: “2020 and early 2021 have seen new research and additional data confirming and consolidating the efficacy and potential of our flagship compound Sepranolone. As we continue forward into an eventful 2021, we remain confident of the significant clinical relevance of Allopregnanolone, and the ability of our flagship compound Sepranolone to suppress Allopregnanolone’s negative, often devastating effects.”

FINANCIAL HIGHLIGHTS

  • R&D expenses remained at 2019 level reflecting strict cost control
  • Staff costs declined following headcount reduction
  • Solid cash position at year-end

R&D HIGHLIGHTS

TOURETTE SYNDROME (TS)

  • Additional positive preclinical data was released in February 2021
  • A preliminary, clean report from the juvenile tox study was received in mid-February 2021 confirming that we are able to dose children and men with Sepranolone for TS.
  • We expect to submit a CTA to the Danish regulatory authorities for our upcoming Phase IIa Tourette syndrome study in the second half of March.
  • We aim to initiate the study in June 2021.

MENSTRUAL MIGRAINE (MM)

  • Our Phase IIa Menstrual Migraine study reached full recruitment in October 2020 with 164 patients recruited.
  • The last patient was randomized on January 14, 2021.
  • The last patient last visit is scheduled for April 20 2021.
  • We are on schedule to publish topline results in June 2021.

PREMENSTRUAL DYSPHORIC DISORDER (PMDD)

  • Additional data from a post hoc analysis of our 2020 Phase IIb PMDD study was presented by our CSO on February 12 2021 at the International Steroid and Nervous System Conference.
  • The findings would be valuable to any larger pharma partner wishing to pursue future PMDD studies, and confirm our confidence in Sepranolone as an effective modulator of Allopregnanolone.
  • The Phase IIb study results and post hoc analysis in its entirety will be submitted for publication before the end of March 2021.

For further information, please contact:

Peter Nordkild, CEO

Phone: +45 25 47 16 46

E-mail: peter.nordkild@asarinapharma.com

Jakob Dynnes Hansen, CFO

Phone: +45 5132 3698

E-mail: jakob.dynnes@asarinapharma.com

Certified Adviser

Erik Penser Bank AB

Phone: +46 8-463 83 00

Mail: certifiedadviser@penser.se

About Asarina Pharma

We are a Swedish biotech company developing Sepranolone for allopregnanolone-related stress, menstrual and neurological disorders. Our product pipeline is built on over 40 years of research into allopregnanolone-related neurological disorders. With our new family of GAMSA compounds (GABAA Modulating Steroid Antagonists) we aim to deliver a new generation of efficacious and safe drugs for still widely untreated neuroendocrinological conditions.

The information above was provided by the CEO of Asarina Pharma AB (publ), for publication on March 15, 1930, 2021.

Tags:

pharmaceutical Neurology clinical studies Tourettes Menstrual Migraine Sepranolone Tourettes syndrom neuroenodrinology

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