New paper using Attana technology for development of therapeutic antibodies against cancer
We are very happy that Attana technology has more or less from the start been involved in taking a malaria parasite protein towards a generic cancer treatment!
The latest work, published in Nature Communications describes that translation into clinical trials turned out to be complicate e.g. by complex manufacturing and expensive scale-up processes of the malaria protein. Converting it into antibodies turned out to be the trick.
Antibody manufacturing is significantly less complicated than protein manufacturing. Attana technology has been applied in this latest stage to secure that the interaction properties for the antibody the malaria protein is similar, even though the actual binding site is decreased from 100 Ångström to 10 Ångström.
The publication shows that:
Two antibodies show therapeutic interaction with the vast majority of cancer cell lines.
The antibodies therapeutic interaction with most tissue biopsies but only limited interaction to healthy tissue, hence low off-target interaction
See our webpage for previous publications, https://www.attana.com/scientific-resources/.
For more information, please contact:
Teodor Aastrup, CEO
ir@attana.com
+46 708 86 23 00
The Board of directors for Attana consider that the information in this press release is not likely to have a significant effect on the share price but is of general interest for the shareholders and hence should be communicated.
About Attana
Attana was founded in 2002 with the vision of in vitro characterization of molecular interactions mimicking in vivo conditions. Since then, Attana has developed proprietary label free biosensors for biochemical, crude, sera, and cell-based assays and the Attana Virus Analytics (AVA) platform, a proprietary in vitro diagnostics (IVD) tool. Attana products and research services are used by Big Pharma, biotech companies and academic institutions within the life sciences. To learn more about our latest services and products, please visit www.attana.com or contact sales@attana.com
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