Concept for a nasal spray vaccine


Photographer: Mia Halleröd Palmgren/Chalmers University of Technology

The researchers aim to design a biomimetic nanoparticle that deceives the body´s immune cells to act as if they had encountered a true virus. In fact, they encounter something known as an mRNA, which is a precursor to a harmless element of the virus. In addition, the artificial particle has been provided with both immune enhancers and a targeting protein – a ‘label’, which acts almost as a set of directions, allowing the vaccine to reach only a certain type of immune cell. When activated, the body will hopefully learn to recognise and defend itself against the virus in the future. The test tube in the picture contains the ´label´.

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Chalmers University of Technology in Gothenburg conducts research and education in technology and natural sciences at a high international level. The university has 3100 employees and 10,000 students, and offers education in engineering, science, shipping and architecture. With scientific excellence as a basis, Chalmers promotes knowledge and technical solutions for a sustainable world. Through global commitment and entrepreneurship, we foster an innovative spirit, in close collaboration with wider society.The EU’s biggest research initiative – the Graphene Flagship – is coordinated by Chalmers. We are also leading the development of a Swedish quantum computer. Chalmers was founded in 1829 and has the same motto today as it did then: Avancez – forward.

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