Hansa Medical receives SEK 3.4 million grant from VINNOVA to carry out Phase II study with IdeS

Hansa Medical has been granted SEK 3.4 million to perform a Phase II-study with the drug candidate IdeS. The grant has been provided within VINNOVA’s (Swedish Governmental Agency for Innovation Systems) Forska&Väx-programme (Research & Growth Programme). VINNOVA states: ”IdeS at kidney transplantation, is a project incorporating high-level competence with strong clinical support within a field of significant medical need”.

”We are very pleased of VINNOVA’s strong support. The SEK 3.4 million will cover the costs of significant parts of seeing IdeS through a Phase II-study. This study will involve patients with renal failure, now waiting for kidney transplantation at Uppsala University Hospital. We seek to file a Phase II application with the Swedish Medical Products Agency subsequent to reporting the results from our on-going Phase I study. Results can be expected to be published in the beginning of 2014,” states Emanuel Björne, CEO of Hansa Medical AB.

VINNOVA Forska & Väx
VINNOVA received 333 applications mounting to a net worth of SEK 410 million. The Forska&Väx-programme targets companies from all industries demonstrating significant potential as to growth and development. Applicants need to showcase a viable international demand for their submitted project, demonstrate its ability to generate growth of the company and its potential to prompt new or better products, services, and processes.

IdeS enables transplantation
Hansa Medical is developing the drug candidate IdeS for treatment in conjunction with kidney transplantation. IdeS is an enzyme targeting and inactivating IgG-antibodies. In a healthy individual, IgG-antibodies constitute a well functioning part of the immune system. However, in several medical conditions IgG-antibodies can cause problems.


For 15 % of patients waiting for kidney transplantation, so-called donor specific antibodies (antibodies hostile to potential donor organ) constitute an immediate barrier for transplantation. Today, there are no efficient methods to reduce antibody levels prior to transplantation. Consequently, these patients rarely, if ever, qualify to be transplanted. Instead, they are referred to years in dialysis, associated with increased risk of infections, cardiovascular diseases and significantly shortened life expectancy.

The drug candidate IdeS carries the potential to become the primary treatment method facilitating transplantation for this group of patients. Estimated market potential point to SEK 1 billion per year in the U.S. and Europe alone.

For further information, please contact:
Hansa Medical AB
Emanuel Björne, CEO
Mobile: 46 707 17 54 77
E-mail: emanuel.bjorne@hansamedical.com
www.hansamedical.com

Hansa Medical pursues clinical development and commercialization of innovative pharmaceuticals and diagnostic methods for the benefit of patients with serious and rare inflammatory diseases. The portfolio includes a marketed diagnostic product, a drug candidate in Phase I trial, and a preclinical research project. Major shareholders are Bo Håkansson via Farstorps Gård AB, and Bengt Ågerup via Nexttobe AB. Hansa Medical is listed on NASDAQ OMX First North (HMED) and Remium Nordic AB is the company’s Certified Adviser.

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About Us

Hansa Medical is a biopharmaceutical company focused on novel immunomodulatory enzymes. Lead project IdeS is an antibody-degrading enzyme in clinical development, with potential use in transplantation and rare autoimmune diseases. Other projects include HBP (a market introduced diagnostic marker for severe sepsis) and EndoS (an antibody-modulating bacterial enzyme in pre-clinical development). The company is based in Lund, Sweden. Hansa Medical's share (HMED) is listed on Nasdaq First North in Stockholm with Remium Nordic AB as Certified Adviser.

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We are very pleased of VINNOVA’s strong support. The SEK 3.4 million will cover the costs of significant parts of seeing IdeS through a Phase II-study. This study will involve patients with renal failure, now waiting for kidney transplantation at Uppsala University Hospital. We seek to file a Phase II application with the Swedish Medical Products Agency subsequent to reporting the results from our on-going Phase I study. Results can be expected to be published in the beginning of 2014.
Emanuel Björne, CEO of Hansa Medical AB