OncoZenge initiates toxicity study and announces modification to the clinical plan
OncoZenge AB (OMX: ONCOZ) has today commenced dosing in a toxicity study for its product candidate BupiZenge[®]. The study design is based on an advisory meeting with the Swedish Medical Agency and aims to document the safety of repeated oral topical administration of bupivacaine.Bupivacaine, which is the active pharmaceutical ingredient in BupiZenge[®], is the most widely used anesthetic for epidural anesthesia during childbirth, as well as for post-operative pain treatment. The compound and its safety profile has been extensively studied since it was first discovered more than sixty years