Scientists Discover Potential Avenue to Treating Type 2 Diabetes at Early Stages
Gene-regulating protein controls fat storage and insulin sensitivity in muscleResearchers at Sanford Burnham Prebys Medical Discovery Institute (SBP) have identified a new potential target for drugs to prevent type 2 diabetes. A paper published today in the Journal of Clinical Investigation shows that blocking a cellular glucose sensor in muscle improves insulin responsiveness.
“Our new study shows that a protein called MondoA may serve as a key link between insulin resistance and accumulation of fat in muscle, which occurs in obesity-related diabetes,” said Daniel P. Kelly, M.D.,