Positive results from Phase IIb benralizumab study in severe asthma published in the Lancet Respiratory Medicine
AstraZeneca today announced that The Lancet Respiratory Medicine has published positive safety and efficacy data from a Phase IIb study evaluating benralizumab, a novel investigational monoclonal antibody, in patients with severe, uncontrolled asthma and elevated levels of eosinophils, a type of inflammatory white blood cell. The study met the primary endpoint, with patients taking benralizumab experiencing a statistically significant reduction in their asthma exacerbation rate versus subjects taking placebo over a period of one year. The study also met the secondary endpoints, with