Tau pathology of the disease is now recognized as an important target for treatment, and it is encouraging that cognitive improvement is seen at such an early stage of the disease with a drug targeting Tau. The field has focused mainly on amyloid as a target for early intervention. Our data are consistent with the evidence that Tau pathology begins at least 20 years before clinical symptoms appear and is a viable first-line target for treatment.
These data support our ability to pursue regulatory submissions. We look forward to making a significant difference addressing this global unmet need with a medication that is affordable, easy to administer, and safe. I’m very pleased to be joining the team and supporting the work we’re undertaking to achieve our mission of bringing treatments to people affected by neurodegenerative diseases caused through protein aggregation – Alzheimer’s is just the beginning.
“We recognise and publicly thank the incredible commitment from participants and partners involved in LUCIDITY. Our scientific focus on the role of tau pathology in neurodegenerative disease with support from our shareholders and team has enabled us to reach this important milestone.”