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  • University of Eastern Finland
    Joensuu / Kuopio
    http://www.uef.fi/en
  • Joensuu Campus
    Yliopistokatu 2 P.O. Box 111 FI-80101 Joensuu
  • Kuopio Campus
    Yliopistonranta 1 P.O. Box 1627 FI-70211 Kuopio
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    Postal code area data can help in the planning of cost-effective health care services

    hen assessing the effects of socioeconomic status (SES) on health inequalities or outcomes of care, it is worthwhile to use small-area-based open data instead of individual SES information, a new study from the University of Eastern Finland shows. Getting access to individual SES information is often a long and expensive process, requiring many different permits. Published in BMC Public Health, the study found that when predicting the treatment outcomes in patients with type 2 diabetes, the effect of small-area-based SES variables is in line with patient-specific individual SES information.

    Risk factors of type 2 diabetes and cardiovascular disease accumulate in children with poor aerobic fitness

    Risk factors of type 2 diabetes and cardiovascular disease accumulate in children who have poor aerobic fitness, a new study from the University of Eastern Finland shows. The study also found that the traditional way of expressing aerobic fitness in proportion to total body mass overestimates the role of aerobic fitness in identifying children at an increased risk of these diseases.   The study was conducted as part of the Physical Activity and Nutrition in Children (PANIC) Study at the University of Eastern Finland, and the findings were reported in the Scandinavian Journal of Medicine &

    Increasing vigorous exercise decreases the risk of type 2 diabetes and cardiovascular disease already in childhood

    Physical exercise can reduce the risk factors of type 2 diabetes and cardiovascular disease even in children, a new study from the University of Eastern Finland shows. In a two-year follow-up of primary school children, sedentary behaviour increased the accumulation of risk factors, whereas increasing the amount of vigorous exercise reduced it. This is one of the first follow-up studies to reliably demonstrate these associations in children. The results are based on follow-up data from the Physical Activity and Nutrition in Children (PANIC) Study, ongoing at the University of Eastern

    Gestational diabetes may predispose to postpartum depression symptoms

    Mothers diagnosed with gestational diabetes mellitus (GDM) have an elevated risk of developing postpartum depression symptoms, according to a new Finnish study. Gestational diabetes mellitus refers to impaired glucose metabolism during pregnancy. Often, mothers with GDM have too high blood glucose levels, and this increases the risk of various adverse effects on the fetus. Moreover, GDM increases the mother’s risk of developing type 2 diabetes later in life. Postpartum depression symptoms are experienced by 10–15 per cent of mothers after childbirth. The newly published study used the

    Self-monitoring of type 2 diabetes reduces follow-up costs by more than half

    Self-monitoring of type 2 diabetes used in combination with an electronic feedback system results in considerable savings on health care costs especially in sparsely populated areas, a new study from the University of Eastern Finland shows. Self-monitoring delivers considerable savings on the overall costs of type 2 diabetes care, as well as on patients’ travel costs. Glycated hemoglobin testing is an important part of managing diabetes, and also a considerable cost item. By replacing half of the required follow-up visits with self-measurements and electronic feedback, the annual total

    Plant protein may protect against type 2 diabetes, meat eaters at greater risk

    A new study from the University of Eastern Finland adds to the growing body of evidence indicating that the source of dietary protein may play a role in the risk of developing type 2 diabetes. The researchers found that plant protein was associated with a lower risk of type 2 diabetes, while persons with a diet rich in meat had a higher risk. The findings were published in the British Journal of Nutrition. Earlier research has linked a high overall intake of protein and animal protein – and eating plenty of processed red meat in particular – with a higher risk of type 2 diabetes. However,

    Intestinal bacteria may protect against diabetes

    A high concentration of indolepropionic acid in the serum protects against type 2 diabetes, shows a new study from the University of Eastern Finland. Indolepropionic acid is a metabolite produced by intestinal bacteria, and its production is boosted by a fibre-rich diet. According to the researchers, the discovery provides additional insight into the role of intestinal bacteria in the interplay between diet, metabolism and health. The findings were published in Scientific Reports. The study was carried out in the LC-MS Metabolomics Centre of the University of Eastern Finland together

    Even mildly excessive body iron stores increase the risk of type 2 diabetes

    Even mildly elevated body iron contributes to the prevalence and incidence of type 2 diabetes, according to research from the University of Eastern Finland. Excess body iron accumulation is a known risk factor of type 2 diabetes in hereditary hemochromatosis, but the results presented by Dr Alex O. Aregbesola in his doctoral thesis show that elevated iron is a risk factor in the general population as well, already at high levels within the normal range. Men accumulate more iron and are more at risk In addition, a gender difference was observed in the risk and prevalence of type 2

    New immune cell subset associated with progression to type 1 diabetes

    A study conducted at the University of Eastern Finland revealed that a recently described T cell subset may have a central role in the development of type 1 diabetes. These so called follicular T helper cells were found to be increased at the onset of type 1 diabetes, and the phenomenon was linked with the presence of autoantibodies commonly associated with the disease. Type 1 diabetes is an autoimmune disease where the immune system destroys the insulin-producing beta cells in the pancreas. Type 1 diabetes typically manifests in childhood and early adolescence. Diabetes-associated

    High serum omega-6 polyunsaturated fatty acid concentrations linked to lower risk of type 2 diabetes

    A new study from the University of Eastern Finland shows that high serum omega-6 polyunsaturated fatty acid concentrations are linked to a significantly reduced risk of type 2 diabetes. The findings were published in the American Journal of Clinical Nutrition. It has been speculated that a high intake of omega-6 polyunsaturated fatty acids may increase the risk of several chronic diseases, as these fatty acids have been suggested to promote low-grade inflammation, among other things. However, studies conducted on humans have not established a link between even a high intake of omega-6

    Obesity and weight loss change splicing pattern of obesity and type 2 diabetes genes

    Alternative splicing of obesity and type 2 diabetes related genes may contribute to the pathophysiology of obesity, according to research from the University of Eastern Finland. Obesity leads to changes in the splicing pattern of metabolically relevant genes such as TCF7L2 and INSR, resulting in impaired insulin action. However, weight loss, induced by either obesity surgery or a very low-calorie diet, reverses these changes. The findings, presented by Dorota Kaminska, MSc, in her doctoral dissertation, increase our understanding of splicing dysregulations in obesity and can result in a new,

    Risk factors associated with overweight cluster already in children

    Lifestyle-related cardiometabolic risk factors cluster already in children in the same way as in adults, according to research from the University of Eastern Finland. A cardiometabolic risk score was used to evaluate cardiometabolic risk in different age groups. The results show that risk factor levels even lower than those generally accepted as risk factor thresholds for type 2 diabetes and atherosclerotic vascular disease are harmful when several risk factors cluster. In addition, a common mutation on the PNPLA3 gene associated with fatty liver in adults was found to be linked to

    Little exercise and heavy use of electronic media constitute a significant health risk for children

    The Physical Activity and Nutrition in Children Study, PANIC, carried out by the Institute of Biomedicine at the University of Eastern Finland shows that low levels of physical activity combined with heavy use of electronic media and sedentary behaviour are linked to an increased risk for type 2 diabetes and vascular diseases already in 6–8 year-old children. The study was published in International Journal of Behavioral Nutrition and Physical Activity, an esteemed journal in the field of exercise and nutrition. Heavy use of electronic media has adverse health effects also in children

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