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  • University of Eastern Finland
    Joensuu / Kuopio
    http://www.uef.fi/en
  • Joensuu Campus
    Yliopistokatu 2 P.O. Box 111 FI-80101 Joensuu
  • Kuopio Campus
    Yliopistonranta 1 P.O. Box 1627 FI-70211 Kuopio
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    Antiepileptic drugs increase risk of Alzheimer’s and dementia

    The use of antiepileptic drugs is associated with an increased risk of Alzheimer’s disease and dementia, according to a new study from the University of Eastern Finland and the German Center for Neurodegenerative Diseases, DZNE. Continuous use of antiepileptic drugs for a period exceeding one year was associated with a 15 percent increased risk of Alzheimer’s disease in the Finnish dataset, and with a 30 percent increased risk of dementia in the German dataset. Some antiepileptic drugs are known to impair cognitive function, which refers to all different aspects of information processing.

    e-Health can support healthy ageing and help preventing cardiovascular disease and dementia in elderly people

    An innovative e-Health solution, based on an interactive Internet platform, has been developed to support senior citizens in improving their lifestyle to prevent cardiovascular disease, cognitive decline and dementia. Researchers from the HATICE trial presented the solution in a pre-press article published in Journal of Alzheimer’s Disease 62(2). The HATICE trial is currently ongoing in Finland, France, and the Netherlands, involving more than 2,500 people aged 65 years or older, at high risk of cardiovascular disease. Half of the participants have access to an Internet platform where

    Scientists uncover why sauna bathing is good for your health

    Over the past couple of years, scientists at the University of Eastern Finland have shown that sauna bathing is associated with a variety of health benefits. Using an experimental setting this time, the research group now investigated the physiological mechanisms through which the heat exposure of sauna may influence a person’s health. Their latest study with 100 test subjects shows that taking a sauna bath of 30 minutes reduces blood pressure and increases vascular compliance, while also increasing heart rate similarly to medium-intensity exercise. Previously, the research group has

    Short and long sleep, and sleep disturbances associated with increased risk of dementia and lung cancer

    Difficulties in initiating or maintaining sleep at middle-age are associated with an increased risk of dementia, according to a new study from the University of Eastern Finland. The 20-year follow-up study was conducted among 2,682 men participating the Kuopio Ischaemic Heart Disease Study. The study participants were aged 42‒60 years at the baseline examinations in 1984‒1989. Shorter or longer sleep than 7–7.5 hours related independently with an increased risk of lung cancer after health behaviour, such as smoking, was taken account of. Additionally, a relationship between higher serum

    Postmenopausal hormone therapy exceeding ten years may protect from dementia

    Postmenopausal estrogen-based hormone therapy lasting longer than ten years was associated with a decreased risk of Alzheimer’s disease in a large study carried out at the University of Eastern Finland. “The protective effect of hormone therapy may depend on its timing: it may have cognitive benefits if initiated at the time of menopause when neurons are still healthy and responsive,” says Bushra Imtiaz, MD, MPH, who presented the results in her doctoral thesis. The study explored the association between postmenopausal hormone replacement therapy, Alzheimer’s disease, dementia and

    Among antidementia drugs, memantine is associated with the highest risk of pneumonia

    A recent study from the University of Eastern Finland shows that among users of antidementia drugs, persons using memantine have the highest risk of pneumonia. The use of rivastigmine patches is associated with an increased risk as well. The study found that persons using donepezil or galantamine had the lowest risk of pneumonia. However, persons using memantine or rivastigmine patches had a 1.6 and 1.15 times higher risk of pneumonia, respectively, but no elevated risk was observed among patients using rivastigmine in capsule form. The real risk increase may be even higher, as only

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