The Singapore Multiethnic Cohort creates a unique research setting to study how to improve the prediction of type 2 diabetes, coronary artery calcification, and changes in cardiovascular risk factors in the Singaporean population. Nightingale’s technology creates a novel opportunity to look at a broad profile of metabolic markers, potentially enhancing the understanding of disease development.
It’s an interesting opportunity to examine how these biomarkers are associated with dietary and other lifestyle factors and may mediate associations between lifestyle factors, cardiovascular disease risk factors, and risk of type 2 diabetes. Moreover, potential biomarker associations can be replicated with other studies around the world carried out using Nightingale’s technology, enabling more detailed analysis of the findings in Singapore.
Nightingale’s blood analysis technology is a global platform. This means that samples measured with our technology all over the world can be combined, compared and replicated. We are excited about this initiative with NUS, as it brings large-scale Southeast Asian sample collections to an international platform, benefitting medical researchers in Singapore and South East Asia but also having a global impact.
Nightingale is committed to continuous improvement and nowhere is this more important than in delivering our clinical service to the highest standard.
From the beginning we’ve put quality and the needs of regulatory requirements at the centre of our strategy.
Chronic diseases are a nightmare, not only for those who suffer from them, but also for those trying to cure them. The EIB is committed to supporting companies like Nightingale that can realistically make a big impact and improve the health of EU citizens. The support of the Investment Plan for Europe is particularly valuable here, and the operation is fully aligned with the objective of supporting high-skilled employment opportunities. This will also enhance Europe’s position as a major leader in medical innovation.
Europe invests heavily in education and science as we believe that putting a strategic effort into these areas can reap huge benefits. This commitment has resulted in Europe’s position today as a world leader in cutting edge medical research. We are delighted that the Investment Plan for Europe is fostering the development of Nightingale’s technology which has the potential to add significant value to European healthcare.
Nightingale wants to create a world where healthcare keeps people healthy throughout their lifetimes, not just whenever they get sick. When we founded Nightingale in 2013, we wanted to bring together innovations from biotechnology, medicine and computer sciences to build a different type of healthcare – one where everyone is given a chance to live a healthier life. Today’s announcement provides Nightingale with the funding needed to take our vision for personalized medicine into European healthcare. By supplying physicians with accurate chronic disease risk prediction for their patients, we will empower people to better understand their own health status and take actions to reduce their risk. Not only will this transform how we treat common diseases such as diabetes and heart disease, but it will also significantly reduce the current economic burden on healthcare systems and workforces.
In addition to treating the symptoms and complications of diseases like type 2 diabetes, we should be equipping people with the best possible tools to keep themselves healthier for longer, and making them available at an affordable price. Virta 360 is a health concept for the 21st century. By combining molecular insights related to physical health with advanced digital health applications that measure lifestyle habits, we can better understand a person’s overall health status and allow them to proactively improve their wellbeing.
An individual’s wellbeing is influenced by all aspects of their life, from nutrition to personal relationships. These are reflected by changes in a person’s blood, providing an indication of their future wellbeing. Virta 360, for the very first time, allows people to fully understand how their lifestyle habits are impacting their health and provides them with better tools to keep their wellbeing on track.
As we have seen in numerous studieswith thousands of study volunteers,GlycA has considerable potential as a marker of chronic inflammation that can effectively predict disease onset and prognosis. The findings of this paper add further evidence to support the measurement of GlycA in national biobanks, as well as its utility in future clinical applications
Nightingale’s mission is strongly linked to scientific evidence generation. This means working with world-leading institutions and biosample collections to continuously improve the understanding of health and disease. Our aim is to translate this understanding into improved early prediction of diabetes and cardiovascular diseases, achieving better healthcare for everyone. Our initiative with the UK Biobank demonstrates Nightingale’s unwavering commitment towards supporting innovative medical science carried out by researchers from across the world.
We are delighted to see these novel blood sample analyses being done in UK Biobank. We already have an enormous amount of information about the lifestyles and genetic make-up of the participants in UK Biobank, as well as about their health, and are currently conducting imaging studies of their brains, hearts and bodies. Providing the medical research community with these additional high quality metabolic biomarker data on such a large scale will enhance discovery science and population science, providing opportunities to benefit patient care and public health.
Analysing 500,000 blood samples from a single study with Nightingale’s comprehensive biomarker profiling technology allows us to uncover metabolic signatures that reflect a risk for future disease onset, as well as their underlying risk factors. We anticipate this detailed molecular readout of the health state, combining both lifestyle and genetic makeup, will result in a wealth of scientific applications from the research community. This will be relevant not only to the British population but also yield ground-breaking science and enhanced drug development opportunities with a global public health impact.
We are excited to be able to expand our metabolomics offerings in the fall of 2018. Our urine, cerebrospinal fluid (CSF) and umbilical cord blood services will allow us to provide researchers with a pervasive and more complete picture of human health. The ability to compare changes in the metabolic profiles of the different bio-fluids is especially interesting and will further the molecular understanding of health and disease.
"We believe that our technology will provide better tools for the prevention of chronic diseases in primary care. Solving the prevailing issues in healthcare today requires the development of cutting-edge innovations and the courage to take advantage of the possibilities they bring. We are honored to receive this award and industry support, as we continue to make strides towards bringing our service to healthcare systems globally.”
We’re proud to have received recognition from the Health Awards jury for our impact on the current debate taking place in the Finnish healthcare sector. As innovators in the healthcare space we aim to switch the primary strategy of the current system from disease treatment to disease prevention, replacing routinely used cholesterol tests worldwide.
It’s an honor to receive recognition from EuropaBio’s jury panel of biotech experts and be invited to speak at the EU parliament. We believe our blood analysis technology has the potential to make a considerable contribution to society through improving early disease detection in healthcare, particularly in primary care. By allowing patients to take an active role in their own health maintenance, we can switch the focus in healthcare from treatment to prevention
"Coronaria aims to build a novel healthcare system in Finland that will benefit all of us, with patients receiving better care, personnel achieving more and society saving money. The emphasis in healthcare must be shifted to preventive and personalized care, especially for chronic disease treatments. We see Nightingale's blood analysis as an important tool to achieve this goal. As a result, we wanted to be the first to pilot the service in Finland",
"The only sustainable way to reduce the burden of chronic diseases is to invest in their prevention. The goal of this cooperative pilot with Coronaria is to prove Nightingale's technology's suitability for routine clinical use"
We believe that our technology takes us one step closer to better prevention of chronic diseases. Therefore, we see this as a notable milestone, not only for our company but also for preventive medicine.
This is an excellent opportunity for us to use Nightingale’s bioanalysis platform, which can provide much more data for a relatively small amount of sample than current methods. Ultimately this data will allow us to better understand and treat chronic conditions.
“We are excited to bring our metabolic profiling technology available on-site at University of Oxford to be utilised for world-class science. The possibility to run routinely and cost-effectively any number of blood samples to gather extensive quantitative metabolic biomarker data creates an unprecedented opportunity for research and clinical applications.