New data on drug metabolism and distribution in the eye
One of the most comprehensive ocular pharmacokinetic studies including metabolism so far provides valuable information for ocular drug development.Severe visual illnesses are increasing in our society, and effective treatments are missing for diseases as age-related macular degeneration, diabetic retinopathy, and glaucoma. Both industry and academia are highly interested to advance ocular drug discovery and development. Ocular pharmacokinetics is a key science in this process, and knowledge of drug metabolism and distribution in the eye is required. However, information on drug-metabolizing