SynAct Pharma submits CTA for Clinical Phase 2b Study in RA
SynAct Pharma AB (“SynAct”) today announced that it has submitted a Clinical Trial Application (CTA) to initiate the clinical Phase 2b study, EXPAND, with the Company’s candidate drug, AP1189, in patients with newly diagnosed rheumatoid arthritis (RA).The EXPAND study is a multicenter, randomized, double-blind, placebo-controlled, 12-week study in newly diagnosed, treatment naïve patients with highly active RA (Clinical Disease Activity Score (CDAI) > 22) who are to start treatment with methotrexate (MTX). EXPAND is a part of SynAct’s strategy to further develop AP1189 in RA patients. In