Researchers identify 12 cell types associated with the pathogenesis of coronary artery disease
A new study from the University of Eastern Finland identified 12 different cell types involved in the pathogenesis of coronary artery disease, CAD. The researchers also showed that the genetic risk factors for CAD take their effect especially via smooth vascular muscle cells, which change their phenotype as the disease progresses. Based on the findings, the researchers devised a risk score system that could help to predict individual risk for CAD and to identify the most appropriate course of treatment in the future. The study was conducted by Professor Minna Kaikkonen-Määttä’s research