Cantargia advances development of nadunolimab in triple negative breast cancer through submission of clinical protocol for TRIFOUR study
Cantargia AB today announced the submission of the clinical trial application for TRIFOUR, a phase Ib/II trial investigating nadunolimab (CAN04) combined with gemcitabine and carboplatin for treatment of triple negative breast cancer (TNBC). After an initial safety lead in, the study will include a randomized phase II part. This trial will be performed in Spain in collaboration with the Spanish Breast Cancer Group, GEICAM. Up to 120 patients may be included and the first patient is estimated to be enrolled in November 2021.The antibody CAN04, binding to interleukin-1 receptor accessory