New gene mutation associated with Fabry cardiomyopathy
The A143T variant of the GLA gene is associated with an increased risk of Fabry cardiomyopathy, according to a new study. The variant plays a role in lipid metabolism. According to the researchers, patients carrying the mutation and manifesting changes in the heart should initiate treatment to prevent the disease from progressing. The study, conducted at the University of Eastern Finland and Kuopio University Hospital, was published in the journal Heart. However, not all carriers of the mutation develop Fabry cardiomyopathy, and the association of the A143T variant with the disease is